Antibiotics, resistome and resistance mechanisms: A bacterial perspective
History of mankind is regarded as struggle against infectious diseases. Rather than
observing the withering away of bacterial diseases, antibiotic resistance has emerged as a …
observing the withering away of bacterial diseases, antibiotic resistance has emerged as a …
Integrons
Integrons are genetic elements able to acquire and rearrange open reading frames (ORFs)
embedded in gene cassette units and convert them to functional genes by ensuring their …
embedded in gene cassette units and convert them to functional genes by ensuring their …
Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration
Conventional CRISPR–Cas systems maintain genomic integrity by leveraging guide RNAs
for the nuclease-dependent degradation of mobile genetic elements, including plasmids and …
for the nuclease-dependent degradation of mobile genetic elements, including plasmids and …
Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli
M Desvaux, G Dalmasso, R Beyrouthy… - Frontiers in …, 2020 - frontiersin.org
Escherichia coli is a versatile bacterial species that includes both harmless commensal
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …
Conjugative and mobilizable genomic islands in bacteria: evolution and diversity
Horizontal transfer of genomic islands (GEIs), that is, chromosomal regions encoding
functions that can be advantageous for the host, plays a key role in bacterial evolution, but …
functions that can be advantageous for the host, plays a key role in bacterial evolution, but …
Core defense hotspots within Pseudomonas aeruginosa are a consistent and rich source of anti-phage defense systems
Bacteria use a diverse arsenal of anti-phage immune systems, including CRISPR-Cas and
restriction enzymes. Recent advances in anti-phage system discovery and annotation tools …
restriction enzymes. Recent advances in anti-phage system discovery and annotation tools …
The chromosomal organization of horizontal gene transfer in bacteria
Bacterial adaptation is accelerated by the acquisition of novel traits through horizontal gene
transfer, but the integration of these genes affects genome organization. We found that …
transfer, but the integration of these genes affects genome organization. We found that …
Hijackers, hitchhikers, or co-drivers? The mysteries of mobilizable genetic elements
Mobile genetic elements shape microbial gene repertoires and populations. Recent results
reveal that many, possibly most, microbial mobile genetic elements require helpers to …
reveal that many, possibly most, microbial mobile genetic elements require helpers to …
Transfer of antibiotic-resistance genes via phage-related mobile elements
Antibiotic resistance is a major concern for society because it threatens the effective
prevention of infectious diseases. While some bacterial strains display intrinsic resistance …
prevention of infectious diseases. While some bacterial strains display intrinsic resistance …
Genomic insights into bifidobacteria
JH Lee, DJ O'Sullivan - Microbiology and Molecular Biology …, 2010 - Am Soc Microbiol
Since the discovery in 1899 of bifidobacteria as numerically dominant microbes in the feces
of breast-fed infants, there have been numerous studies addressing their role in modulating …
of breast-fed infants, there have been numerous studies addressing their role in modulating …