Antiretroviral therapy (ART), while essential in combatting tuberculosis (TB) and HIV
coinfection, is often complicated by the TB-associated immune reconstitution inflammatory …

Calprotectin (CLP) is a heterodimer formed by two S-100 calcium-binding cytosolic proteins,
S100A8 and S100A9. It is a multifunctional protein expressed mainly by neutrophils and …

The lethal combination involving TB and HIV, known as “syndemic” diseases, synergistically
act upon one another to magnify the disease burden. Individuals on anti-retroviral therapy …

Background Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis is one
of the top thirteen causes of death worldwide. The major challenge to control TB is the …

IRIS is a common complication in HIV-infected patients treated for tuberculosis (TB) and
cART. Our aim was to evaluate NK cell reconstitution in HIV-infected patients with TB-IRIS …

Objective This study aims to evaluate plasma S100A9 levels in tuberculosis (TB) patients
with admission to the ICU as a marker to predict the risk of death for pulmonary severe TB …

This chapter discusses the natural history of Tuberculosis (TB) and virulence factors, and
then focuses on the major new developments in the pathogenesis of TB. Acquired immunity …

Background Syphilis is a sexually transmitted disease that threatens human health
worldwide. However, the immune regulation cascade caused by treponemia pallidum (TP) …

Aicardi-Goutières syndrome (AGS) is a rare genetic pediatric disorder currently associated
with mu-tations in 9 genes (TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1 …

The lethal combination involving TB and HIV, known as' syndemic'diseases synergistically
act upon one another to magnify the disease burden. Individuals on ART are at risk of …