During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …

Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Infections caused by the fungal pathogen Aspergillus fumigatus are increasingly resistant to
first-line azole antifungal drugs. However, despite its clinical importance, little is known …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Antifungal resistance represents a major clinical challenge to clinicians responsible for
treating invasive fungal infections due to the limited arsenal of systemically available …

Chronic pulmonary aspergillosis (CPA) is an uncommon and problematic pulmonary
disease, complicating many other respiratory disorders, thought to affect∼ 240 000 people …

Abstract The European Society for Clinical Microbiology and Infectious Diseases, the
European Confederation of Medical Mycology and the European Respiratory Society Joint …

Aspergillus fumigatus is an opportunistic human pathogen that causes aspergillosis, a
spectrum of environmentally acquired respiratory illnesses. It has a cosmopolitan distribution …

The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

The clinical presentation of Aspergillus lung disease is determined by the interaction
between fungus and host. Invasive aspergillosis develops in severely immunocompromised …