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Review on plant antimicrobials: a mechanistic viewpoint
Microbial resistance to classical antibiotics and its rapid progression have raised serious
concern in the treatment of infectious diseases. Recently, many studies have been directed …
concern in the treatment of infectious diseases. Recently, many studies have been directed …
Antimicrobials from medicinal plants: an emergent strategy to control oral biofilms
Oral microbial biofilms, directly related to oral diseases, particularly caries and periodontitis,
exhibit virulence factors that include acidification of the oral microenvironment and the …
exhibit virulence factors that include acidification of the oral microenvironment and the …
Caffeic acid prevents vascular oxidative stress and atherosclerosis against atherosclerogenic diet in rats
Diet and lifestyle play a crucial role in the progress of some cardiovascular disorders
(CVDs). Rising interest in natural products and their pharmacological investigations …
(CVDs). Rising interest in natural products and their pharmacological investigations …
An assessment of the in vitro models and clinical trials related to the antimicrobial activities of phytochemicals
J Kopel, J McDonald, A Hamood - Antibiotics, 2022 - mdpi.com
An increased number antibiotic-resistant bacteria have emerged with the rise in antibiotic
use worldwide. As such, there has been a growing interest in investigating novel antibiotics …
use worldwide. As such, there has been a growing interest in investigating novel antibiotics …
Repurposing of statins for Buruli Ulcer treatment: antimicrobial activity against Mycobacterium ulcerans
J Dominguez, AI Mendes, AR Pacheco… - Frontiers in …, 2023 - frontiersin.org
Mycobacterium ulcerans causes Buruli Ulcer, a neglected infectious skin disease that
typically progresses from an early non-ulcerative lesion to an ulcer with undermined edges …
typically progresses from an early non-ulcerative lesion to an ulcer with undermined edges …
Pharmacometabolomics for the study of lipid-lowering therapies: opportunities and challenges
E Gianazza, M Brioschi, A Iezzi, G Paglia… - International Journal of …, 2023 - mdpi.com
Lipid-lowering therapies are widely used to prevent the development of atherosclerotic
cardiovascular disease (ASCVD) and related mortality worldwide.“Omics” technologies have …
cardiovascular disease (ASCVD) and related mortality worldwide.“Omics” technologies have …
Repurposing of Fluvastatin against Candida albicans CYP450 lanosterol 14 α-demethylase, a target enzyme for antifungal therapy: an In silico and In vitro study
R Rana, R Sharma, A Kumar - Current molecular medicine, 2019 - ingentaconnect.com
Background: The incidence of fungal infections has increased significantly. Specifically the
cases of candida albicans infection are increasing day by day and their resistance to …
cases of candida albicans infection are increasing day by day and their resistance to …
Insights into the pivotal role of statins and its nanoformulations in hyperlipidemia
Hyperlipidemia is the primary cause of heart disorders and has been manifested as the
condition with remarkable higher levels of very-low-density lipoproteins, low-density …
condition with remarkable higher levels of very-low-density lipoproteins, low-density …
Tamoxifen twists again: On and off-targets in macrophages and infections
C Sfogliarini, G Pepe, A Dolce, S Della Torre… - Frontiers in …, 2022 - frontiersin.org
Beyond the wide use of tamoxifen in breast cancer chemotherapy due to its estrogen
receptor antagonist activity, this drug is being assayed in repurposing strategies against a …
receptor antagonist activity, this drug is being assayed in repurposing strategies against a …
Tamoxifen from chemotherapy to antiviral drug: Possible activity against COVID-19
Tamoxifen (TAM) is the oldest and the most-prescribed selective estrogen receptor
modulator (SERM). It is a member of the triphenylethylene group. TAM has been used to …
modulator (SERM). It is a member of the triphenylethylene group. TAM has been used to …