Polymeric gels for intravaginal drug delivery
MT Cook, MB Brown - Journal of Controlled Release, 2018 - Elsevier
Intravaginal drug delivery can elicit a local effect, or deliver drugs systemically without
hepatic first pass metabolism. There are a number of emerging areas in intravaginal drug …
hepatic first pass metabolism. There are a number of emerging areas in intravaginal drug …
Long-acting approaches for delivery of antiretroviral drugs for prevention and treatment of HIV: a review of recent research
Introduction Despite significant advances in treatment and prevention of HIV-1 infection,
poor adherence to daily combination antiretroviral therapy (ART) regimens remains a major …
poor adherence to daily combination antiretroviral therapy (ART) regimens remains a major …
Disulfiram 3D printed film produced via hot-melt extrusion techniques as a potential anticervical cancer candidate
Cervical cancer is known globally as one of the most common health problems in women.
Indeed, one of the most convenient approaches for its treatment is an appropriate …
Indeed, one of the most convenient approaches for its treatment is an appropriate …
Montmorillonite-based polyacrylamide hydrogel rings for controlled vaginal drug delivery
Vaginal drug delivery is regarded as a promising route against women-related health issues
such as unwanted pregnancies and sexually transmitted infections. However, only a very …
such as unwanted pregnancies and sexually transmitted infections. However, only a very …
Manufacturing and examination of vaginal drug delivery system by FDM 3D printing
Vaginal drug delivery systems can provide a long-term and constant liberation of the active
pharmaceutical ingredient even for months. For our experiment, FDM 3D printing was used …
pharmaceutical ingredient even for months. For our experiment, FDM 3D printing was used …
Microbicide vaginal rings: Technological challenges and clinical development
RK Malcolm, PJ Boyd, CF McCoy, DJ Murphy - Advanced drug delivery …, 2016 - Elsevier
Vaginal rings (VRs) are flexible, torus-shaped, polymeric devices designed to sustain
delivery of pharmaceutical drugs to the vagina for clinical benefit. Following first report in a …
delivery of pharmaceutical drugs to the vagina for clinical benefit. Following first report in a …
Women-specific routes of administration for drugs: A critical overview
The woman's body presents a number of unique anatomical features that can constitute
valuable routes for the administration of drugs, either for local or systemic action. These are …
valuable routes for the administration of drugs, either for local or systemic action. These are …
HIV-1 reverse transcriptase and antiviral drug resistance. Part 2
Highlights•Discrimination and excision are major NRTI resistance mechanisms.•NRTIs used
in combination select different resistance mutations.•Complexes of NNRTI with RT-DNA in …
in combination select different resistance mutations.•Complexes of NNRTI with RT-DNA in …
Intravaginal rings as delivery systems for microbicides and multipurpose prevention technologies
AR Thurman, MR Clark, JA Hurlburt… - International journal of …, 2013 - Taylor & Francis
There is a renewed interest in delivering pharmaceutical products via intravaginal rings
(IVRs). IVRs are flexible torus-shaped drug delivery systems that can be easily inserted and …
(IVRs). IVRs are flexible torus-shaped drug delivery systems that can be easily inserted and …
Long-acting antiretrovirals: where are we now?
AN Nyaku, SG Kelly, BO Taiwo - Current HIV/AIDS Reports, 2017 - Springer
Abstract Purpose of Review Current HIV treatment options require daily use of combination
antiretroviral drugs. Many persons living with HIV experience treatment fatigue and …
antiretroviral drugs. Many persons living with HIV experience treatment fatigue and …