Barriers and enablers for deprescribing benzodiazepine receptor agonists in older adults: a systematic review of qualitative and quantitative studies using the …

P Evrard, C Pétein, JB Beuscart, A Spinewine - Implementation Science, 2022 - Springer
Background Many strategies aimed at deprescribing benzodiazepine receptor agonists
(BZRA) in older adults have already been evaluated with various success rates. There is so …

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety disorders in adults

E Van Leeuwen, ML van Driel… - Cochrane Database …, 2021 - cochranelibrary.com
Background Depression and anxiety are the most frequent indication for which
antidepressants are prescribed. Long‐term antidepressant use is driving much of the …

Antipsychotics for agitation and psychosis in people with Alzheimer's disease and vascular dementia

V Mühlbauer, R Möhler, MN Dichter… - Cochrane Database …, 2021 - cochranelibrary.com
Background Typical and atypical antipsychotics are widely used to treat agitation and
psychosis in dementia. However, whether or not they are beneficial is uncertain. Some trials …

Antipsychotic deprescription for older adults in long-term care: the HALT study

H Brodaty, L Aerts, F Harrison, T Jessop… - Journal of the American …, 2018 - Elsevier
Objectives Despite limited efficacy and significant safety concerns, antipsychotic
medications are frequently used to treat behavioral and psychological symptoms of …

Variation in use of antipsychotic medications in nursing homes in the United States: A systematic review

H Cioltan, S Alshehri, C Howe, J Lee, M Fain, H Eng… - BMC geriatrics, 2017 - Springer
Background The use of antipsychotic medications (APMs) in nursing home residents in the
US is an increasingly prominent issue and has been associated with increased risk of …

Approaches to deprescribing psychotropic medications for changed behaviours in long-term care residents living with dementia

SL Harrison, M Cations, T Jessop, SN Hilmer, M Sawan… - Drugs & aging, 2019 - Springer
Psychotropic medications have a high risk of serious adverse events and small effect size for
changed behaviours for people with dementia. Non-pharmacological approaches are …

[HTML][HTML] Less is more: the impact of deprescribing psychotropic drugs on behavioral and psychological symptoms and daily functioning in nursing home patients …

MH Gedde, BS Husebo, J Mannseth, RLS Kjome… - The American Journal of …, 2021 - Elsevier
Objective To investigate the impact of medication reviews using collegial mentoring and
systematic clinical evaluation on psychotropic prescriptions, behavioral and psychological …

[HTML][HTML] Associations between pain and depression in nursing home patients at different stages of dementia

A Erdal, E Flo, G Selbaek, D Aarsland, S Bergh… - Journal of affective …, 2017 - Elsevier
Background Pain is associated with depression in nursing home patients with dementia. It is,
however, unclear whether pain increases depression. Therefore we evaluated the …

Interventions to optimize medication use in nursing homes: a narrative review

A Spinewine, P Evrard, C Hughes - European Geriatric Medicine, 2021 - Springer
Purpose Polypharmacy, medication errors and adverse drug events are frequent among
nursing home residents. Errors can occur at any step of the medication use process. We …

Persistent use of psychotropic drugs in nursing home residents in Norway

AS Helvik, J Šaltytė Benth, B Wu, K Engedal, G Selbæk - BMC geriatrics, 2017 - Springer
Background The prevalence of psychotropic drug (PTD) use in NH residents is high, but few
have explored prevalence and persistency in PTD in NH residents and factors associated …