About a half a century has passed since dopamine was identified as a neurotransmitter, and
it has been several decades since it was established that people with Parkinson's disease …

The present work reviews research on the learning and skilled performance of movement
sequences in Parkinson's disease (PD). We focus specifically on the serial reaction time …

People with Parkinson disease (PD) who show freezing of gait also have dysfunction in
cognitive domains that interact with mobility. Specifically, freezing of gait is associated with …

Freezing of gait (FoG) is a disabling symptom associated with falls, with little or no
responsiveness to pharmacological treatment. Current protocols used for rehabilitation are …

Dopaminergic medication in Parkinson׳ s disease has been proposed to improve cognitive
processing by modulating the severely depleted dorsal striatum, while impairing reward …

Though the cerebellum has been previously implicated in explicit sequence learning, the
exact role of this structure in the acquisition of motor skills is not completely clear. The …

While the cerebellum contributes to nonmotor task performance, the specific contributions of
the structure remain unknown. One possibility is that the cerebellum allows for the offloading …

Objectives: Many animal and a few human studies have reported on the neural connectivity
of the substantia nigra (SN) and the ventral tegmental area (VTA). However, it has not been …

Previous research investigating motor sequence learning (MSL) and consolidation in
patients with Parkinson's disease (PD) has predominantly included heterogeneous …

Objective: This study aimed to systematically review the effects of currently prescribed
antiparkinson medication on cognition in patients with mild-to-moderate Parkinson's disease …