The widespread use of molecular machines in biology has long suggested that great
rewards could come from bridging the gap between synthetic molecular systems and the …

A grand challenge in the fields of chemistry and materials science is the ability to construct f
the plac or a giv ement of en application. each component in or materials with absolute …

Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

Motor proteins are nature's solution for directing movement at the molecular level. The field
of artificial molecular motors takes inspiration from these tiny but powerful machines …

DNA nanotechnology has emerged as a powerful tool to precisely design and control
molecular circuits, machines and nanostructures. A major goal in this field is to build devices …

The specificity and predictability of Watson–Crick base pairing make DNA a powerful and
versatile material for engineering at the nanoscale. This has enabled the construction of a …

We describe a simple and robust method to construct complex three-dimensional (3D)
structures by using short synthetic DNA strands that we call “DNA bricks.” In one-step …

The widespread use of controlled molecular‐level motion in key natural processes suggests
that great rewards could come from bridging the gap between the present generation of …

We introduce the concept of hybridization chain reaction (HCR), in which stable DNA
monomers assemble only upon exposure to a target DNA fragment. In the simplest version …

INTRODUCTION Since the 1980s, the design and synthesis of molecular machines has
been identified as a grand challenge for molecular engineering. Robots are an important …