Metal coordinated pyrrole-based macrocycles as contrast agents for magnetic resonance imaging technologies: Synthesis and applications

MJF Calvete, SMA Pinto, MM Pereira… - Coordination Chemistry …, 2017 - Elsevier
The number of scientific reports on the field of imaging in biomedical sciences is rising
massively, with the emergence of “noninvasive” in vivo imaging technologies, of which …

Thermodynamic stability, kinetic inertness and relaxometric properties of monoamide derivatives of lanthanide (III) DOTA complexes

L Tei, Z Baranyai, L Gaino, A Forgács, A Vágner… - Dalton …, 2015 - pubs.rsc.org
A complete thermodynamic and kinetic solution study on lanthanide (III) complexes with
monoacetamide (DOTAMA, L1) and monopropionamide (DOTAMAP, L2) derivatives of …

Gold nanoparticles functionalised with stable, fast water exchanging Gd 3+ chelates as high relaxivity contrast agents for MRI

MF Ferreira, B Mousavi, PM Ferreira, CIO Martins… - Dalton …, 2012 - pubs.rsc.org
Gold nanoparticles functionalized with Gd3+ chelates displaying fast water exchange,
superb pH stability and inertness towards transmetalation with Zn2+ have been prepared …

Complexes of bifunctional DO3A-N-(α-amino) propinate ligands with Mg (II), Ca (II), Cu (II), Zn (II), and lanthanide (III) ions: thermodynamic stability, formation and …

Z Garda, T Kócs, I Bányai, JA Martins, FK Kálmán… - Molecules, 2021 - mdpi.com
The thermodynamic, kinetic, and structural properties of Ln3+ complexes with the
bifunctional DO3A-ACE4− ligand and its amide derivative DO3A-BACE4−(modelling the …

Gold nanoparticles functionalised with fast water exchanging Gd 3+ chelates: Linker effects on the relaxivity

MF Ferreira, J Gonçalves, B Mousavi, MIM Prata… - Dalton …, 2015 - pubs.rsc.org
The relaxivity displayed by Gd3+ chelates immobilized onto gold nanoparticles is the result
of the complex interplay between the nanoparticle size, the water exchange rate and the …

MRI-visible polymer based on poly (methyl methacrylate) for imaging applications

M Younis, V Darcos, C Paniagua, P Ronjat, L Lemaire… - RSC …, 2016 - pubs.rsc.org
Macromolecular contrast agents are very attractive to afford efficient magnetic resonance
imaging (MRI) visualization of implantable medical devices. In this work, we report on the …

Ln [DO3A-N-α-(pyrenebutanamido) propionate] complexes: optimized relaxivity and NIR optical properties

MF Ferreira, G Pereira, AF Martins, CIO Martins… - Dalton …, 2014 - pubs.rsc.org
We have proposed recently that the DO3A-N-α-(amino) propionate chelator and its amide
conjugates are leads to targeted, high relaxivity, safe contrast agents for magnetic …

[HTML][HTML] Multifunctionalization of cyanuric chloride for the stepwise synthesis of potential multimodal imaging chemical entities

MJF Calvete, SMA Pinto, HD Burrows… - Arabian Journal of …, 2020 - Elsevier
We report a synthetic strategy to combine different moieties in a single structure using
cyanuric chloride (2, 4, 6-trichlorotriazine) as a starting platform for preparing potential …

Modular imaging agents containing amino acids and peptides

HF Schmitthenner, S Beach, T Barrett… - US Patent …, 2020 - Google Patents
Targeted molecular imaging agents (TMIAs) are derived from coupling together pre-formed
amino acids with imag ing agents attached to their side chains. These peptide-based …

Ga [NO2A-N-(α-amino) propionate] chelates: synthesis and evaluation as potential tracers for 68 Ga PET

MF Ferreira, G Pereira, JP André, MIM Prata… - Dalton …, 2014 - pubs.rsc.org
The availability of commercial 68Ge/68Ga cyclotron-independent 68Ga3+ generators is
making Positron Emission Tomography (PET) accessible to most hospitals, which is …