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Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine
FJ Vizoso, N Eiro, S Cid, J Schneider… - International journal of …, 2017 - mdpi.com
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …
their capacity for local engrafting and differentiating into multiple tissue types. However …
Conditioned medium–is it an undervalued lab waste with the potential for osteoarthritis management?
Background The approaches currently used in osteoarthritis (OA) are mainly short-term
solutions with unsatisfactory outcomes. Cell-based therapies are still controversial (in terms …
solutions with unsatisfactory outcomes. Cell-based therapies are still controversial (in terms …
Alginate/gelatin encapsulation promotes NK cells differentiation potential of bone marrow resident C-kit+ hematopoietic stem cells
The ability of natural killer (NK) cells to destroy cancerous cells with no prior sensitization
has made them attractive candidates for cell therapy. The application of hydrogels must be …
has made them attractive candidates for cell therapy. The application of hydrogels must be …
[HTML][HTML] Silver nanoparticles induce the cardiomyogenic differentiation of bone marrow derived mesenchymal stem cells via telomere length extension
Finding new strategies for the treatment of heart failures using stem cells has attracted a lot
of attention. Meanwhile, nanotechnology-based approaches to regenerative medicine …
of attention. Meanwhile, nanotechnology-based approaches to regenerative medicine …
[HTML][HTML] 3D-MSCs A151 ODN-loaded exosomes are immunomodulatory and reveal a proteomic cargo that sustains wound resolution
Introduction Non-healing wounds remain a major burden due to the lack of effective
treatments. Mesenchymal stem cell-derived exosomes (MSC-Exo) have emerged as …
treatments. Mesenchymal stem cell-derived exosomes (MSC-Exo) have emerged as …
Mesenchymal stem cells promote caspase-3 expression of SH-SY5Y neuroblastoma cells via reducing telomerase activity and telomere length
Objective (s): The use of mesenchymal stem cells in malignancies has attracted much
attention due to their ability to deliver anticancer agents to tumors, including cytokines …
attention due to their ability to deliver anticancer agents to tumors, including cytokines …
Synthesis and in vitro evaluation of thermosensitive hydrogel scaffolds based on (PNIPAAm-PCL-PEG-PCL-PNIPAAm)/Gelatin and (PCL-PEG-PCL)/Gelatin for use in …
Background: Biodegradable thermosensitive hydrogel scaffolds based on novel three-block
PCL-PEG-PCL and penta block PNIPAAm-PCL-PEG-PCL-PNIPAAm copolymers blended …
PCL-PEG-PCL and penta block PNIPAAm-PCL-PEG-PCL-PNIPAAm copolymers blended …
[HTML][HTML] Application of advanced nanomaterials for kidney failure treatment and regeneration
The implementation of nanomedicine not only provides enhanced drug solubility and
reduced off-target adverse effects, but also offers novel theranostic approaches in clinical …
reduced off-target adverse effects, but also offers novel theranostic approaches in clinical …
Polymeric hydrogels as mesenchymal stem cell secretome delivery system in biomedical applications
Secretomes of mesenchymal stem cells (MSCs) have been successfully studied in
preclinical models for several biomedical applications, including tissue engineering, drug …
preclinical models for several biomedical applications, including tissue engineering, drug …
[HTML][HTML] Umbilical cord MSCs and their secretome in the therapy of arthritic diseases: a research and industrial perspective
C Arrigoni, D D'Arrigo, V Rossella, C Candrian… - Cells, 2020 - mdpi.com
The prevalence of arthritic diseases is increasing in developed countries, but effective
treatments are currently lacking. The injection of mesenchymal stem cells (MSCs) represents …
treatments are currently lacking. The injection of mesenchymal stem cells (MSCs) represents …