Recombinant proteins (RP) are widely used as biopharmaceuticals, industrial enzymes, or
sustainable food source. Yeasts, with their ability to produce complex proteins through a …

Since the mid-1960s, methylotrophic yeast Komagataella phaffii (previously described as
Pichia pastoris) has received increasing scientific attention. The interest for the industrial …

Besides its use for efficient production of recombinant proteins the methylotrophic yeast
Pichia pastoris (syn. Komagataella spp.) has been increasingly employed as a platform to …

The methylotrophic yeast Pichia pastoris is firmly established as a host for the production of
recombinant proteins, frequently outperforming other heterologous hosts. Already, a …

The methylotrophic yeast Pichia pastoris (syn. Komagataella spp.) is one of the most
important production systems for heterologous proteins. After the first genome sequences …

The disaccharide trehalose plays a crucial role in multiple facets of the stress biology of
yeasts and fungi. Here, we evaluate the properties, cellular and ecophysiological roles …

The current transition towards the circular bioeconomy requires a rational development of
biorefineries to sustainably fulfill the present demands. The use of Komagataella phaffii …

Biomanufacturing is emerging as a key technology for the sustainable production of
chemicals, materials, and food ingredients using engineered microbes. However, despite …

Culture medium heterogeneity is inherent in industrial bioreactors. The loss of mixing
efficiency in a large-scale bioreactor yields to the formation of concentration gradients …

The methylotrophic yeast Pichia pastoris (Komagataella spp.) is widely used as cell factory
for recombinant protein production. In the past recent years, important breakthroughs in the …