Cancer displays high levels of heterogeneity and mutation potential, and curing cancer
remains a challenge that clinicians and researchers are eager to overcome. In recent years …

As rates of Cesarean delivery and common non-communicable disorders (NCDs), such as
obesity, metabolic disease, and atopy/asthma, have concomitantly increased in recent …

Early nutritional exposures, including during embryogenesis and the immediate postnatal
period, affect offspring outcomes in both the short-and long-term. Alterations of these …

Fewer than 20% of all clinical trials are conducted in low-and middle-income countries
(LMICs) where the disease burden is highest. This commentary focuses on why some …

Recently, the intrauterine sterile environment theory has been questioned. Growing
evidence shows that microbial in utero pioneer gut colonization could occur prebirth, and …

Increasingly, it is appreciated that the neonatal enteric microbiome and the human host are
intricately connected with alterations in each affecting the other. This chapter discusses the …

The neonatal period is critical in the development of the microbiome and the gastrointestinal
tract. That is, the microbiome regulates not only the processes that are associated with the …

BACKGROUND Periodontitis during pregnancy is associated with an increased risk of
preterm birth (< 37 weeks of gestation) or low birthweight (< 2500 g) offspring. Beyond …

The metabolome and lipidome comprise the thousands of molecular compounds in an
organism. Molecular compounds consist of the upstream metabolic components of …

Neonatal intestinal failure is a complex medical condition that is associated with the need for
long term parenteral nutrition and its associated complications. The microbiome in this …