Parietal cells are responsible for gastric acid secretion, which aids in the digestion of food,
absorption of minerals, and control of harmful bacteria. However, a fine balance of activators …

The adenosine A2b receptor is a G-protein coupled receptor. Its activation occurs with high
extracellular adenosine concentration, for example in inflammation or hypoxia. These …

Composed by a molecule of adenine and a molecule of ribose, adenosine is a paradigm of
recyclable nucleoside with a multiplicity of functions that occupies a privileged position in the …

Adenosine (ADO), generated by the ectonucleotidase CD39 and CD73 from ATP, interacts
with its specific G protein-coupled receptors, which can impair anti-tumor immune responses …

Gastric ulcers significantly impact the quality of life of patients, the pathogenesis of which is
closely associated with Helicobacter pylori (HP) infection. Oxidative stress is involved in the …

Adenosine is readily available to the glandular epithelium of the stomach. Formed
continuously in intracellular and extracellular locations, it is notably produced from ATP …

The regulation of gastric HCl secretion by the parietal cell occurs primarily through the
regulated recycling of H, K-ATPase. Secretagogue stimulation of the parietal cell initiates …

Engevik AC, Kaji I, Goldenring JR. The Physiology of the Gastric Parietal Cell. Physiol Rev
100: 573–602, 2020. First published October 31, 2019; doi: 10.1152/physrev. 00016.2019 …