Invasive brain–machine interfaces can restore motor, sensory and cognitive functions.
However, their clinical adoption has been hindered by the surgical risk of implantation and …

Implantable intracortical microelectrodes can record a neuron's rapidly changing action
potentials (spikes). In vivo neural activity recording methods often have either high temporal …

Brain-machine interfaces hold promise for the restoration of sensory and motor function and
the treatment of neurological disorders, but clinical brain-machine interfaces have not yet …

The use of implants that can electrically stimulate or record electrophysiological or
neurochemical activity in nervous tissue is rapidly expanding. Despite remarkable results in …

Brain-machine interfaces (BMIs) combine methods, approaches, and concepts derived from
neurophysiology, computer science, and engineering in an effort to establish real-time …

In the mammalian nervous system, billions of neurons connected by quadrillions of
synapses exchange electrical, chemical and mechanical signals. Disruptions to this network …

Advancements in neurotechnologies for electrophysiology, neurochemical sensing,
neuromodulation, and optogenetics are revolutionizing scientific understanding of the brain …

Brain function depends on simultaneous electrical, chemical and mechanical signaling at
the cellular level. This multiplicity has confounded efforts to simultaneously measure or …

Optogenetic interrogation of neural pathways relies on delivery of light-sensitive opsins into
tissue and subsequent optical illumination and electrical recording from the regions of …

Implantable biosensors are valuable scientific tools for basic neuroscience research and
clinical applications. Neurotechnologies provide direct readouts of neurological signal and …