The emerging role of regulatory cell-based therapy in autoimmune disease
F Ghobadinezhad, N Ebrahimi, F Mozaffari… - Frontiers in …, 2022 - frontiersin.org
Autoimmune disease, caused by unwanted immune responses to self-antigens, affects
millions of people each year and poses a great social and economic burden to individuals …
millions of people each year and poses a great social and economic burden to individuals …
Mechanisms of immune suppression by myeloid-derived suppressor cells: the role of interleukin-10 as a key immunoregulatory cytokine
Chronic immune activation and inflammation are unwanted consequences of many
pathological conditions, since they could lead to tissue damage and immune exhaustion …
pathological conditions, since they could lead to tissue damage and immune exhaustion …
Interleukin-10 produced by myeloid-derived suppressor cells is critical for the induction of Tregs and attenuation of rheumatoid inflammation in mice
Myeloid-derived suppressor cells (MDSCs) are heterogenous populations of immature
myeloid progenitor cells with immunoregulatory function. MDSCs play critical roles in …
myeloid progenitor cells with immunoregulatory function. MDSCs play critical roles in …
GM-CSF: An immune modulatory cytokine that can suppress autoimmunity
GM-CSF was originally identified as a colony stimulating factor (CSF) because of its ability to
induce granulocyte and macrophage populations from precursor cells. Multiple studies have …
induce granulocyte and macrophage populations from precursor cells. Multiple studies have …
Myeloid-derived suppressor cells: ductile targets in disease
FM Consonni, C Porta, A Marino, C Pandolfo… - Frontiers in …, 2019 - frontiersin.org
Myeloid-derived suppressor cells (MDSCs) represent a heterogeneous population of
immature myeloid cells with major regulatory functions and rise during pathological …
immature myeloid cells with major regulatory functions and rise during pathological …
The immunosuppressive activity of myeloid-derived suppressor cells in murine Paracoccidioidomycosis relies on Indoleamine 2, 3-dioxygenase activity and Dectin-1 …
Paracoccidioidomycosis (PCM) is a systemic mycosis with a high incidence in Latin
America. Prior studies have demonstrated the significance of the enzyme Indoleamine 2, 3 …
America. Prior studies have demonstrated the significance of the enzyme Indoleamine 2, 3 …
Myeloid‐derived suppressor cells induce the expansion of regulatory B cells and ameliorate autoimmunity in the sanroque mouse model of systemic lupus …
Objective This study was undertaken to assess the effect of myeloid‐derived suppressor
cells (MDSCs) on various B cell subsets, including regulatory B cells, as well as to assess …
cells (MDSCs) on various B cell subsets, including regulatory B cells, as well as to assess …
Beyond immunosuppressive effects: dual roles of myeloid-derived suppressor cells in bone-related diseases
Z Ling, C Yang, J Tan, C Dou, Y Chen - Cellular and Molecular Life …, 2021 - Springer
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature
myeloid cells (IMCs) with immunosuppressive functions, whereas IMCs originally …
myeloid cells (IMCs) with immunosuppressive functions, whereas IMCs originally …
Myeloid-derived suppressor cells in transplantation: the dawn of cell therapy
W Zhang, J Li, G Qi, G Tu, C Yang, M Xu - Journal of translational …, 2018 - Springer
Myeloid-derived suppressor cells (MDSCs) are a series of innate cells that play a significant
role in inhibiting T cell-related responses. This heterogeneous population of immature cells …
role in inhibiting T cell-related responses. This heterogeneous population of immature cells …
Myeloid-derived suppressor cells are associated with impaired Th1 and Th17 responses and severe pulmonary paracoccidioidomycosis which is reversed by anti-Gr1 …
Previous studies on paracoccidioidomycosis (PCM), the most prevalent systemic mycosis in
Latin America, revealed that host immunity is tightly regulated by several suppressive …
Latin America, revealed that host immunity is tightly regulated by several suppressive …