Metagenomics is a discipline that enables the genomic study of uncultured microorganisms.
Faster, cheaper sequencing technologies and the ability to sequence uncultured microbes …

Transposons make up the bulk of eukaryotic genomes, but are difficult to annotate because
they evolve rapidly. Most of the unannotated portion of sequenced genomes is probably …

One of the greatest challenges facing the cognitive sciences is to explain what it means to
know a language, and how the knowledge of language is acquired. The dominant approach …

Cyanobacteria of the genera Synechococcus and Prochlorococcus are important
contributors to photosynthetic productivity in the open ocean. The discovery of genes (psbA …

Determining the functional role (s) of enzymes is very important to build the metabolic
blueprint of an organism and to identify the potential roles enzymes may play in metabolic …

The human gut is populated by a rich and diverse microbiota that has been described as a
human metabolic organ. Its composition has an impact on the health status of the host and …

Sequence-based approach for motif prediction is of great interest and remains a challenge.
In this work, we develop a local combinational variable approach for sequence-based helix …

Motivation: Assessing the false positive rate of function prediction methods is difficult, as it is
hard to establish that a protein does not have a certain function. To determine to what extent …

Background Predicting the function of a protein from its sequence is a long-standing
challenge of bioinformatic research, typically addressed using either sequence-similarity or …

It has recently been shown (Kunik et al., PLOS Comput Biol 2007; 3 (8): e167) that the
occurrence of specific peptides (SPs) on sequences of enzymes allows for accurate EC …