Azathioprine, a purine antimetabolite immunosuppressant, photosensitizes the skin and
causes the production of mutagenic reactive oxygen species. It is postulated to increase the …

Post-transplant malignancy is recognised as being a major limitation to the success of solid
organ transplantation and it is currently considered one of the unavoidable costs of long …

Objective Induction of malignancy is a major concern when rheumatoid arthritis (RA) is
treated with biologic therapy. A meta‐analysis of RA biologic clinical trials found a general …

Importance Solid-organ transplant recipients (SOTRs) are at greater risk of develo** some
cancers than the general population; however, because they are also at increased risk of …

Abstract Development of cancer is a feared, and increasingly apparent, complication of long-
term immunosuppressive therapy in transplant recipients. In addition to the need to reduce …

Cancer stem cell (CSC) biology and tumor immunology have shaped our understanding of
tumorigenesis. However, we still do not fully understand why tumors can be contained but …

BACKGROUND: Previous studies have documented humoral and cell-mediated
immunologic defects in patients with vitiligo. OBJECTIVE: This 24-week study assessed the …

Post‐transplant de novo malignancies are reviewed in three time periods:(i) the azathioprine
(AZA) era from 1962 to 1980–1981,(ii) the cyclosporine (CYA) era (1980 to present) in which …

Abstract Purpose of Review Despite the improvement in medical therapy for heart failure
and the advancements in mechanical circulatory support, heart transplantation (HT) still …

VITILIGO IS A RELATIVELY COM-mon, acquired pigmentary disorder characterized by
areas of depigmented skin resulting from loss of epidermal melanocytes. The prevalence of …