Quantitative susceptibility map**: current status and future directions

EM Haacke, S Liu, S Buch, W Zheng, D Wu… - Magnetic resonance …, 2015 - Elsevier
Quantitative susceptibility map** (QSM) is a new technique for quantifying magnetic
susceptibility. It has already found various applications in quantifying in vivo iron content …

Iron and Alzheimer's disease: from pathology to imaging

D Tran, P DiGiacomo, DE Born… - Frontiers in Human …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a debilitating brain disorder that afflicts millions worldwide with
no effective treatment. Currently, AD progression has primarily been characterized by …

Measuring iron in the brain using quantitative susceptibility map** and X-ray fluorescence imaging

W Zheng, H Nichol, S Liu, YCN Cheng, EM Haacke - Neuroimage, 2013 - Elsevier
Measuring iron content in the brain has important implications for a number of
neurodegenerative diseases. Quantitative susceptibility map** (QSM), derived from …

Pathogenic implications of distinct patterns of iron and zinc in chronic MS lesions

BF Popescu, JM Frischer, SM Webb, M Tham… - Acta …, 2017 - Springer
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS) in which oligodendrocytes, the CNS cells that stain most robustly for …

Quantitative susceptibility map** as an imaging biomarker for Alzheimer's disease: The expectations and limitations

Y Uchida, H Kan, K Sakurai, K Oishi… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most common type of dementia and a distressing diagnosis
for individuals and caregivers. Researchers and clinical trials have mainly focused on β …

[HTML][HTML] Methods for quantitative susceptibility and R2* map** in whole post-mortem brains at 7T applied to amyotrophic lateral sclerosis

C Wang, S Foxley, O Ansorge… - Neuroimage, 2020 - Elsevier
Susceptibility weighted magnetic resonance imaging (MRI) is sensitive to the local
concentration of iron and myelin. Here, we describe a robust image processing pipeline for …

Iron heterogeneity in early active multiple sclerosis lesions

M Tham, JM Frischer, SD Weigand… - Annals of …, 2021 - Wiley Online Library
Objective Multiple sclerosis (MS) is a heterogeneous inflammatory demyelinating disease.
Iron distribution is altered in MS patients' brains, suggesting iron liberation within active …

Rehabilitation augments hematoma clearance and attenuates oxidative injury and ion dyshomeostasis after brain hemorrhage

MR Williamson, K Dietrich, MJ Hackett, S Caine… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—We assessed the elemental and biochemical effects of
rehabilitation after intracerebral hemorrhage, with emphasis on iron-mediated oxidative …

Matching ex vivo MRI With Iron Histology: Pearls and Pitfalls

A De Barros, G Arribarat, J Combis… - Frontiers in …, 2019 - frontiersin.org
Iron levels in the brain can be estimated using newly developed specific magnetic
resonance imaging (MRI) sequences. This technique has several applications, especially in …

[HTML][HTML] Map** iron in human heart tissue with synchrotron x-ray fluorescence microscopy and cardiovascular magnetic resonance

MJ House, AJ Fleming, MD de Jonge… - Journal of …, 2014 - Elsevier
Background MRI assessment of cardiac iron is particularly important for assessing
transfusion-dependent anaemia patients. However, comparing the iron distribution from …