The biological olfactory system is the sensory system responsible for the detection of the
chemical composition of the environment. Several attempts to mimic biological olfactory …

The acute loss of taste and smell following COVID-19 are hallmark symptoms that affect 20–
85% of patients. However, the pathophysiology and potential treatments of COVID-19 smell …

Comparative analysis can provide important insights into complex biological systems. As
demonstrated in the accompanying paper, translating ribosome affinity purification (TRAP) …

The main focus for the development of adenosine targets as analgesics to date has been A
1 Rs due to its antinociceptive profile in various preclinical pain models. The usefulness of …

It is well known that the nucleoside adenosine exerts a modulatory influence in the central
nervous system by activating G protein coupled receptors. Adenosine A2A receptors, the …

In the central nervous system (CNS), adenosine is an important neuromodulator and
regulates neuronal and non-neuronal cellular function (eg microglia) by actions on …

In the pursuit of improved treatments for Parkinson's disease (PD), the adenosine A2A
receptor has emerged as an attractive nondopaminergic target. Based on the compelling …

Caffeine, a non-selective adenosine receptor antagonist, has been suggested as a potential
drug to counteract age-related cognitive decline since critical changes in adenosinergic …

Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting
approximately 1% of the population older than 60 years. Classically, PD is considered to be …

Introduction 3. Basic aspects of adenosine as a neuromodulator relevant for cognitive
functions 4. Effects of adenosine receptor antagonists on cognitive deficits in aged rodents …