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The roles of extracellular vesicles in the immune system
The twenty-first century has witnessed major developments in the field of extracellular
vesicle (EV) research, including significant steps towards defining standard criteria for the …
vesicle (EV) research, including significant steps towards defining standard criteria for the …
Regulation of cargo selection in exosome biogenesis and its biomedical applications in cancer
Extracellular vesicles (EVs), including exosomes, are increasingly recognized as potent
mediators of intercellular communication due to their capacity to transport a diverse array of …
mediators of intercellular communication due to their capacity to transport a diverse array of …
Exploiting the biogenesis of extracellular vesicles for bioengineering and therapeutic cargo loading
Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …
applications in various diseases. These natural nanoparticles benefit from favorable safety …
The exosome journey: from biogenesis to uptake and intracellular signalling
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
[HTML][HTML] The role of cancer-associated fibroblasts in cancer invasion and metastasis
Simple Summary Cancer metastasis is often associated with a dismal prognosis for the
patient. It is, therefore, crucial to understand the mechanisms behind the cascade of events …
patient. It is, therefore, crucial to understand the mechanisms behind the cascade of events …
Extracellular vesicles: mediators of intercellular communication in tissue injury and disease
Intercellular communication is a critical process that ensures cooperation between distinct
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …
Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling
Cancer immunotherapies have shown clinical success in various types of tumors but the
patient response rate is low, particularly in breast cancer. Here we report that malignant …
patient response rate is low, particularly in breast cancer. Here we report that malignant …
Basophil activation test: mechanisms and considerations for use in clinical trials and clinical practice
The basophil activation test (BAT) is a functional assay that measures the degree of
degranulation following stimulation with allergen or controls by flow cytometry. It correlates …
degranulation following stimulation with allergen or controls by flow cytometry. It correlates …
[HTML][HTML] Exosome-derived microRNAs of human milk and their effects on infant health and development
BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
The tissue origin effect of extracellular vesicles on cartilage and bone regeneration
Q Li, H Yu, M Sun, P Yang, X Hu, Y Ao, J Cheng - Acta Biomaterialia, 2021 - Elsevier
Direct implantation of mesenchymal stem cells (MSCs) for cartilage and bone tissue
engineering faces challenges, such as immune rejection and loss of cellular viability or …
engineering faces challenges, such as immune rejection and loss of cellular viability or …