[HTML][HTML] Imaging perivascular space structure and function using brain MRI

G Barisano, KM Lynch, F Sibilia, H Lan, NC Shih… - Neuroimage, 2022 - Elsevier
In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …

The etiology and evolution of magnetic resonance imaging-visible perivascular spaces: Systematic review and meta-analysis

SV Okar, F Hu, RT Shinohara, ES Beck… - Frontiers in …, 2023 - frontiersin.org
Objectives Perivascular spaces have been involved in neuroinflammatory and
neurodegenerative diseases. Upon a certain size, these spaces can become visible on …

Paving the way to better understand the effects of prolonged spaceflight on operational performance and its neural bases

AC Stahn, D Bucher, P Zu Eulenburg, P Denise… - npj …, 2023 - nature.com
Abstract Space exploration objectives will soon move from low Earth orbit to distant
destinations like Moon and Mars. The present work provides an up-to-date roadmap that …

A critical guide to the automated quantification of perivascular spaces in magnetic resonance imaging

W Pham, M Lynch, G Spitz, T O'Brien… - Frontiers in …, 2022 - frontiersin.org
The glymphatic system is responsible for waste clearance in the brain. It is comprised of
perivascular spaces (PVS) that surround penetrating blood vessels. These spaces are filled …

Longitudinal changes in cerebral perfusion, perivascular space volume, and ventricular volume in a healthy cohort undergoing a spaceflight analog

JB Tidwell, JA Taylor, HR Collins… - American Journal …, 2023 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: A global decrease in brain perfusion has recently been
reported during exposure to a ground-based spaceflight analog. Considering that CSF and …

Effects of spaceflight on the brain

RD Seidler, XW Mao, GD Tays, T Wang… - The Lancet …, 2024 - thelancet.com
The number of long duration human spaceflights has increased substantially over the past
15 years, leading to the discovery of numerous effects on the CNS. Microgravity results in …

Robust, fully-automated assessment of cerebral perivascular spaces and white matter lesions: a multicentre MRI longitudinal study of their evolution and association …

G Barisano, M Iv, J Choupan, M Hayden-Gephart… - …, 2025 - thelancet.com
Background Perivascular spaces (PVS) on brain MRI are surrogates for small parenchymal
blood vessels and their perivascular compartment, and may relate to brain health. However …

Methods for assessing change in brain plasticity at night and psychological resilience during daytime between repeated long-duration space missions

K Otsuka, G Cornelissen, Y Kubo, K Shibata… - Scientific reports, 2023 - nature.com
This study was designed to examine the feasibility of analyzing heart rate variability (HRV)
data from repeat-flier astronauts at matching days on two separate missions to assess any …

Automated methods for detecting and quantitation of enlarged perivascular spaces on MRI

J Moses, B Sinclair, M Law, TJ O'Brien… - Journal of Magnetic …, 2023 - Wiley Online Library
The brain's glymphatic system is a network of intracerebral vessels that function to remove
“waste products” such as degraded proteins from the brain. It comprises of the vasculature …

Diffusion tensor image analysis ALong the perivascular space (DTI-ALPS): revisiting the meaning and significance of the method

T Taoka, R Ito, R Nakamichi, T Nakane… - … Resonance in Medical …, 2024 - jstage.jst.go.jp
The ALPS-index was found to be an indicator of a number of conditions related to the
glymphatic system. Thus, although this was expected in the original report, the results of the …