Protein arginine methyltransferases (PRMTs) are emerging as attractive therapeutic targets.
PRMTs regulate transcription, splicing, RNA biology, the DNA damage response and cell …

Arginine methylation is a common post-translational modification functioning as an
epigenetic regulator of transcription and playing key roles in pre-mRNA splicing, DNA …

Transfer RNA (tRNA)‐derived small RNAs (tsRNAs) have recently emerged as important
regulators of protein translation and shown to have diverse biological functions. However …

Protein arginine methyltransferase 6 (PRMT6) is a type I PRMT that is involved in epigenetic
regulation of gene expression through methylating histone or non-histone proteins, and …

A remarkable post-transitional modification of both histones and non-histone proteins is
arginine methylation. Methylation of arginine residues is crucial for a wide range of cellular …

Abstract Protein Arginine Methyltransferases (PRMTs) are a family of enzymes regulating
protein arginine methylation, which is a post-translational modification crucial for various …

Cell type specification relies on the capacity of undifferentiated cells to properly respond to
specific differentiation-inducing signals. Using genomic approaches along with loss-and …

The methylation of arginine residues by protein arginine methyltransferases (PRMTs) is a
type of post-translational modification which is important for numerous cellular processes …

The development of vertebrate neurons requires a change in membrane
phosphatidylcholine (PC) metabolism. Although PC hydrolysis is essential for enhanced …

Among the nine mammalian protein arginine methyltransferases (PRMTs), PRMT8 is
unusual because it has restricted expression in the nervous system and is the only …