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Endocytosis at the nanoscale
I Canton, G Battaglia - Chemical Society Reviews, 2012 - pubs.rsc.org
Endocytosis is a fundamental process in which eukaryotic cells internalise molecules and
macromolecules via deformation of the membrane and generation of membrane-bound …
macromolecules via deformation of the membrane and generation of membrane-bound …
Polymeric vesicles in biomedical applications
Polymeric vesicles, or polymersomes, are nano-to micrometre sized polymeric capsules with
a bilayered membrane. Applications of these vesicles are foreseen in nanomedicine, in vivo …
a bilayered membrane. Applications of these vesicles are foreseen in nanomedicine, in vivo …
Layer‐by‐layer‐assembled capsules and films for therapeutic delivery
Polymeric materials formed via layer‐by‐layer (LbL) assembly have promise for use as drug
delivery vehicles. These multilayered materials, both as capsules and thin films, can …
delivery vehicles. These multilayered materials, both as capsules and thin films, can …
Beyond the lipid-bilayer: interaction of polymers and nanoparticles with membranes
M Schulz, A Olubummo, WH Binder - Soft Matter, 2012 - pubs.rsc.org
Membranes can be fabricated either from lipid or polymer molecules, leading to the
formation of liposomes or polymersomes. In all types of liposomal membranes, the issue of …
formation of liposomes or polymersomes. In all types of liposomal membranes, the issue of …
Polymersomes spanning from nano-to microscales: advanced vehicles for controlled drug delivery and robust vesicles for virus and cell mimicking
Polymersomes provide a highly promising platform for mimicking biological membranes as
well as for controlled delivery of various pharmaceuticals and biopharmaceuticals. The …
well as for controlled delivery of various pharmaceuticals and biopharmaceuticals. The …
Polymersomes and their applications in cancer delivery and therapy
Polymersomes have been proposed as a platform for drug delivery systems since late 90s.
They are exploited to deliver hydrophilic and/or hydrophobic therapeutic and diagnostic …
They are exploited to deliver hydrophilic and/or hydrophobic therapeutic and diagnostic …
Efficient Encapsulation of Plasmid DNA in pH‐Sensitive PMPC–PDPA Polymersomes: Study of the Effect of PDPA Block Length on Copolymer–DNA Binding Affinity
We report the self‐assembly of a series of amphiphilic diblock copolymers comprising a
biocompatible, hydrophilic block, poly (2‐methacryloyloxyethyl phosphorylcholine)(PMPC) …
biocompatible, hydrophilic block, poly (2‐methacryloyloxyethyl phosphorylcholine)(PMPC) …
Aqueous Self‐Assembly of Purely Hydrophilic Block Copolymers into Giant Vesicles
Self‐assembly of macromolecules is fundamental to life itself, and historically, these systems
have been primitively mimicked by the development of amphiphilic systems, driven by the …
have been primitively mimicked by the development of amphiphilic systems, driven by the …
Molecular engineering of polymersome surface topology
Biological systems exploit self-assembly to create complex structures whose arrangements
are finely controlled from the molecular to mesoscopic level. We report an example of using …
are finely controlled from the molecular to mesoscopic level. We report an example of using …
Polymersomes: a synthetic biological approach to encapsulation and delivery
M Massignani, H Lomas, G Battaglia - Modern techniques for nano-and …, 2010 - Springer
Compartmentalization, ie the ability to create controlled volumes and separate molecules
one from another is possibly the most important requisite for complex manipulations. Indeed …
one from another is possibly the most important requisite for complex manipulations. Indeed …