Doxorubicin—an agent with multiple mechanisms of anticancer activity

M Kciuk, A Gielecińska, S Mujwar, D Kołat… - Cells, 2023 - mdpi.com
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …

Recent preclinical and clinical progress in liposomal doxorubicin

K Aloss, P Hamar - Pharmaceutics, 2023 - mdpi.com
Doxorubicin (DOX) is a potent anti-cancer agent that has garnered great interest in research
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …

Effective adsorption of doxorubicin hydrochloride on zirconium metal-organic framework: equilibrium, kinetic and thermodynamic studies

GAA AlHazmi, KS AbouMelha, MG El-Desouky… - Journal of Molecular …, 2022 - Elsevier
Zirconium metal organic framework (Zr-MOF) has been synthesized by hydrothermal method
and various spectroscopic methods were used to characterize the samples. The adsorption …

[HTML][HTML] Biological interactions of carbon-based nanomaterials: From coronation to degradation

K Bhattacharya, SP Mukherjee, A Gallud… - … , Biology and Medicine, 2016 - Elsevier
Carbon-based nanomaterials including carbon nanotubes, graphene oxide, fullerenes and
nanodiamonds are potential candidates for various applications in medicine such as drug …

Efficient toxic doxorubicin hydrochloride removal from aqueous solutions using facial alumina nanorods

GH Al-Hazmi, MS Refat, KF Alshammari… - Journal of Molecular …, 2023 - Elsevier
A simple synthesis method was used for successfully preparing mesoporous alumina
nanorods. The new mesoporous alumina nanorods were illustrated by several …

Applications of nanoscale metal–organic frameworks as imaging agents in biology and medicine

FD Duman, RS Forgan - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Nanoscale metal–organic frameworks (NMOFs) are an interesting and unique class of
hybrid porous materials constructed by the self-assembly of metal ions/clusters with organic …

METTL3 promotes adriamycin resistance in MCF-7 breast cancer cells by accelerating pri-microRNA-221-3p maturation in a m6A-dependent manner

X Pan, X Hong, S Li, P Meng, F **ao - Experimental & molecular …, 2021 - nature.com
Breast cancer (BC) is the most prevalent malignant neoplasm among women and is the fifth
most common cause of cancer-associated death worldwide. Acquired chemoresistance …

Doxorubicin-loaded composite nanogels for cancer treatment

M Mohammadi, L Arabi, M Alibolandi - Journal of Controlled Release, 2020 - Elsevier
Nanogels as a versatile vehicle for doxorubicin have attracted great attention during the last
decade. Since a nanogel composite device transport encapsulated drugs to the site of action …

Tumor targeting via integrin ligands

UK Marelli, F Rechenmacher, TRA Sobahi… - Frontiers in …, 2013 - frontiersin.org
Selective and targeted delivery of drugs to tumors is a major challenge for an effective
cancer therapy and also to overcome the side-effects associated with current treatments …

Exosome‐mediated transfer of long noncoding RNA H19 induces doxorubicin resistance in breast cancer

X Wang, X Pei, G Guo, X Qian, D Dou… - Journal of cellular …, 2020 - Wiley Online Library
Abstract Development of the acquired resistance is one major obstacle during
chemotherapy for cancer patients. Exosomes mediate intercellular communication and …