Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic
compounds, have attracted tremendous attention from researchers worldwide since the 19th …

The synthesis of heterocycles is an emerging area of chemical research considering their
high importance in pharmaceuticals, material chemistry, and natural product synthesis. The …

In this study, we describe the direct insertion of an intramolecular nitrogen atom into an
aromatic C–C bond. In this transformation, carbamoyl azides are activated by a Rh catalyst …

The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

Quinazolinones, an important class of fused heterocyclic alkaloids has attracted high
attention in organic and medicinal chemistry due to their significant and wide range of …

Nitrogen-rich heterocycles, particularly quinazolines and quinazolinones, represent a
unique class of diversified frameworks displaying a broad spectrum of biological functions …

In the past two decades, transition metal-catalyzed C–H functionalization followed by
annulations with various coupling partners has received much attention in organic synthesis …

Emergence of drug resistance has created unmet medical need for the development of new
classes of antibiotics. Discovery of new antibacterial agents with new mode of action …

Carbodiimides are a unique class of heterocumulene compounds that display distinctive
chemical properties. The rich chemistry of carbodiimides has drawn increasing attention …

Piperazine is one of the most sought heterocyclics for the development of new drug
candidates. This ring can be traced in a number of well established, commercially available …