Pirates of the haemoglobin

D Akinbosede, R Chizea, SA Hare - Microbial Cell, 2022 - pmc.ncbi.nlm.nih.gov
Not all treasure is silver and gold; for pathogenic bacteria, iron is the most precious and the
most pillaged of metallic elements. Iron is essential for the survival and growth of all life; …

The ligand effect resulted in different fluorescence responses of two similar zinc-based MOFs to high-valence metal ions and amino acids

Q Hu, JL Liu, QM Zheng, JF Chang, LZ Wu… - Microporous and …, 2021 - Elsevier
The strategy of ligand functionalization can be used to adjust and control the properties of
Metal-Organic Frameworks (MOFs). Based on these considerations, we chose two similar …

Molecular basis of hemoglobin binding and heme removal in Corynebacterium diphtheriae

BJ Mahoney, LR Lyman, J Ford, J Soule… - Proceedings of the …, 2025 - pnas.org
To successfully mount infections, nearly all bacterial pathogens must acquire iron, a key
metal cofactor that primarily resides within human hemoglobin. Corynebacterium …

The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme–iron from human hemoglobin

R Macdonald, BJ Mahoney, J Soule, AK Goring… - Proceedings of the …, 2023 - pnas.org
Streptococcus pyogenes (group A Streptococcus) is a clinically important microbial
pathogen that requires iron in order to proliferate. During infections, S. pyogenes uses the …

Magnetic relaxometry of methemoglobin by widefield nitrogen-vacancy microscopy

S Lamichhane, EC Guevara, I Fescenko… - Applied Physics …, 2024 - pubs.aip.org
Hemoglobin (Hb) is a multifaceted protein, classified as a metalloprotein, chromoprotein,
and globulin. It incorporates iron, which plays a crucial role in transporting oxygen within red …

The Staphylococcus aureus IsdH receptor forms a dynamic complex with human hemoglobin that triggers heme release via two distinct hot spots

K Ellis-Guardiola, J Clayton, C Pham… - Journal of molecular …, 2020 - Elsevier
Iron is an essential nutrient that is actively acquired by bacterial pathogens during infections.
Clinically important Staphylococcus aureus obtains iron by extracting heme from …

Proline isomerization modulates the bacterial IsdB/hemoglobin interaction: an atomic force spectroscopy study

F Pancrazi, O De Bei, F Lavecchia di Tocco… - Discover Nano, 2025 - Springer
Iron surface determinant B (IsdB), a Staphylococcus aureus (SA) surface protein involved in
both heme iron acquisition from host hemoglobin (Hb) and bacterial adhesion, is a proven …