Aggregation-induced emission photosensitizer-based photodynamic therapy in cancer: from chemical to clinical

Z Meng, H Xue, T Wang, B Chen, X Dong… - Journal of …, 2022 - Springer
Cancer remains a serious threat to human health owing to the lack of effective treatments.
Photodynamic therapy (PDT) has emerged as a promising non-invasive cancer treatment …

The 2019 mathematical oncology roadmap

RC Rockne, A Hawkins-Daarud, KR Swanson… - Physical …, 2019 - iopscience.iop.org
Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology,
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …

Surgery-mediated tumor-promoting effects on the immune microenvironment

X Cheng, H Zhang, A Hamad, H Huang… - Seminars in cancer …, 2022 - Elsevier
Surgical resection continues to be the mainstay treatment for solid cancers even though
chemotherapy and immunotherapy have significantly improved patient overall survival and …

[HTML][HTML] Mathematical modeling of radiotherapy and its impact on tumor interactions with the immune system

RA Bekker, S Kim, S Pilon-Thomas, H Enderling - Neoplasia, 2022 - Elsevier
Radiotherapy is a primary therapeutic modality widely utilized with curative intent.
Traditionally tumor response was hypothesized to be due to high levels of cell death …

Implantable, 3D-printed alginate scaffolds with bismuth sulfide nanoparticles for the treatment of local breast cancer via enhanced radiotherapy

B Colak, YN Ertas - ACS Applied Materials & Interfaces, 2024 - ACS Publications
Surgical removal of tumor tissue remains the primary clinical approach for addressing breast
cancer; however, complete tumor excision is challenging, and the remaining tumor cells can …

Neoadjuvant therapy for breast cancer as a model for translational research

C Selli, AH Sims - Breast cancer: basic and clinical research, 2019 - journals.sagepub.com
Neoadjuvant therapy, where patients receive systemic therapy before surgical removal of
the tumour, can downstage tumours allowing breast-conserving surgery, rather than …

Knowledge gaps in oncoplastic breast surgery

WP Weber, M Morrow, J de Boniface, A Pusic… - The Lancet …, 2020 - thelancet.com
The aims of the Oncoplastic Breast Consortium initiative were to identify important
knowledge gaps in the field of oncoplastic breast-conserving surgery and nipple-sparing or …

[HTML][HTML] Preoperative radio (chemo) therapy in breast cancer: time to switch the perspective?

A Montero, R Ciérvide - Current Oncology, 2022 - mdpi.com
Aim: Radiation therapy represents, together with surgery and systemic treatment, the triad on
which the current management of patients with breast cancer is based, achieving high …

The optimal radiation dose to induce robust systemic anti-tumor immunity

J Poleszczuk, H Enderling - International journal of molecular sciences, 2018 - mdpi.com
The synergy of radiation and the immune system is currently receiving significant attention in
oncology as numerous studies have shown that cancer irradiation can induce strong anti …

Hypoxia and perfusion in breast cancer: simultaneous assessment using PET/MR imaging

JC Carmona-Bozo, R Manavaki, R Woitek… - European …, 2021 - Springer
Objectives Hypoxia is associated with poor prognosis and treatment resistance in breast
cancer. However, the temporally variant nature of hypoxia can complicate interpretation of …