The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications
B Zingales, MA Miles, DA Campbell… - Infection, genetics and …, 2012 - Elsevier
The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …
nature for millions of years. The human infection, named Chagas disease, is a major public …
Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity
B Zingales - Acta tropica, 2018 - Elsevier
The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete ty** units (DTUs) …
widely recognized. At present, T. cruzi is partitioned into seven discrete ty** units (DTUs) …
Randomized trial of benznidazole for chronic Chagas' cardiomyopathy
CA Morillo, JA Marin-Neto, A Avezum… - … England Journal of …, 2015 - Mass Medical Soc
Background The role of trypanocidal therapy in patients with established Chagas'
cardiomyopathy is unproven. Methods We conducted a prospective, multicenter …
cardiomyopathy is unproven. Methods We conducted a prospective, multicenter …
Chagas disease in the United States: a public health approach
Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …
Pathogen diversity, immunity, and the fate of infections: lessons learned from Trypanosoma cruzi human–host interactions
The complexity of host–pathogen interactions often leads to distinct clinical outcomes upon
infection with different pathogen strains. In this Review, we explore the interactions between …
infection with different pathogen strains. In this Review, we explore the interactions between …
Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease
Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
Chagas Disease Ecology in the United States: Recent Advances in Understanding Trypanosoma cruzi Transmission Among Triatomines, Wildlife, and Domestic …
Chagas disease, a neglected tropical disease present in the Americas, is caused by the
parasite Trypanosoma cruzi and is transmitted by triatomine kissing bug vectors. Hundreds …
parasite Trypanosoma cruzi and is transmitted by triatomine kissing bug vectors. Hundreds …
The epidemiology of Chagas disease in the Americas
ZM Cucunubá, SA Gutiérrez-Romero… - The Lancet Regional …, 2024 - thelancet.com
Chagas disease is a complex parasitic zoonosis that still threatens public health across the
Americas. Initiatives to control Trypanosoma cruzi transmission via blood transfusion and …
Americas. Initiatives to control Trypanosoma cruzi transmission via blood transfusion and …
Poverty, migration, and Chagas disease
Abstract Purpose of Review Chagas disease is among the most serious problems for public
health in Latin America. Although the causative agent Trypanosoma cruzi and its triatomine …
health in Latin America. Although the causative agent Trypanosoma cruzi and its triatomine …
[HTML][HTML] Towards the establishment of a consensus real-time qPCR to monitor Trypanosoma cruzi parasitemia in patients with chronic Chagas disease …
Quantitative real-time PCR (qPCR) is an accurate method to quantify Trypanosoma cruzi
DNA and can be used to follow-up parasitemia in Chagas disease (CD) patients undergoing …
DNA and can be used to follow-up parasitemia in Chagas disease (CD) patients undergoing …