Obesity and breast cancer: a case of inflamed adipose tissue

R Kolb, W Zhang - Cancers, 2020 - mdpi.com
Obesity is associated with an increased risk of estrogen receptor-positive breast cancer in
postmenopausal women and a worse prognosis for all major breast cancer subtypes …

Impact of the different preparation methods to obtain human adipose-derived stromal vascular fraction cells (AD-SVFs) and human adipose-derived mesenchymal …

P Gentile, C Calabrese, B De Angelis… - International journal of …, 2019 - mdpi.com
Autologous therapies using adipose-derived stromal vascular fraction (AD-SVFs) and adult
adipose-derived mesenchymal stem cells (AD-MSCs) warrant careful preparation of the …

Potential pro-tumorigenic effect of bisphenol A in breast cancer via altering the tumor microenvironment

Y Kwon - Cancers, 2022 - mdpi.com
Simple Summary Bisphenol A (BPA) is primarily used to produce polycarbonate plastics,
such as water bottles. Exposure to BPA has been shown to increase the growth of breast …

Obese adipose tissue as a driver of breast cancer growth and development: update and emerging evidence

P Bhardwaj, KA Brown - Frontiers in Oncology, 2021 - frontiersin.org
Obesity is an established risk factor for breast cancer growth and progression. A number of
advances have been made in recent years revealing new insights into this link. Early events …

Intratumoral adipocyte-high breast cancer enrich for metastatic and inflammation-related pathways but associated with less cancer cell proliferation

Y Tokumaru, M Oshi, E Katsuta, L Yan… - International journal of …, 2020 - mdpi.com
Cancer-associated adipocytes are known to cause inflammation, leading to cancer
progression and metastasis. The clinicopathological and transcriptomic data from 2256 …

Proteins found in the triple-negative breast cancer secretome and their therapeutic potential

PR McHenry, JR Prosperi - International Journal of Molecular Sciences, 2023 - mdpi.com
The cancer secretome comprises factors secreted by tumors, including cytokines, growth
factors, proteins from the extracellular matrix (ECM), proteases and protease inhibitors …

Three-dimensional breast cancer model to investigate CCL5/CCR1 expression mediated by direct contact between breast cancer cells and adipose-derived stromal …

M Watzling, L Klaus, T Weidemeier, H Horder, R Ebert… - Cancers, 2023 - mdpi.com
Simple Summary In breast cancer, adipose-derived stromal cells (ASCs) and adipocytes, as
components of the mammary fat pad, come into close contact with tumor cells. To …

Cellular interactions in tumor microenvironment during breast cancer progression: new frontiers and implications for novel therapeutics

T Akinsipe, R Mohamedelhassan, A Akinpelu… - Frontiers in …, 2024 - frontiersin.org
The breast cancer tumor microenvironment (TME) is dynamic, with various immune and non-
immune cells interacting to regulate tumor progression and anti-tumor immunity. It is now …

[HTML][HTML] Yin Yang 1 facilitates hepatocellular carcinoma cell lipid metabolism and tumor progression by inhibiting PGC-1β-induced fatty acid oxidation

Y Li, V Kasim, X Yan, L Li, ITS Meliala, C Huang, Z Li… - Theranostics, 2019 - ncbi.nlm.nih.gov
Lipid accumulation is a driving force in tumor development, as it provides tumor cells with
both energy and the building blocks of phospholipids for construction of cell membranes …

Focal adhesion kinase fine tunes multifaced signals toward breast cancer progression

DC Rigiracciolo, F Cirillo, M Talia, L Muglia, JS Gutkind… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is the most common diagnosed malignancy and the main
leading cause of tumor-related death among women worldwide. Thus, several studies have …