Cell wall damage increases macromolecular crowding effects in the Escherichia coli cytoplasm

T Pittas, W Zuo, AJ Boersma - Iscience, 2023 - cell.com
The intracellular milieu is crowded with biomacromolecules. Macromolecular crowding
changes the interactions, diffusion, and conformations of biomacromolecules. Changes in …

FRET-FISH probes chromatin compaction at individual genomic loci in single cells

A Mota, S Berezicki, E Wernersson, L Harbers… - Nature …, 2022 - nature.com
Chromatin compaction is a key biophysical property that influences multiple DNA
transactions. Lack of chromatin accessibility is frequently used as proxy for chromatin …

A novel genetic fluorescent reporter to visualize mitochondrial nucleoids

J Deng, L Swift, M Zaman, F Shahhosseini, A Sharma… - bioRxiv, 2023 - biorxiv.org
Mitochondria have their own genome (mtDNA), which is present in hundreds of copies per
cell and organized into nucleoid structures that are distributed throughout the dynamic …