In this review article we examine the role of glutathione reductase in the regulation,
modulation and maintenance of cellular redox homoeostasis. Glutathione reductase is …

This review answers the question of why selenium is such an important trace element in the
human diet. Daily dietary intake of selenium and its content in various food products is …

Abstract Background The liver fluke Fasciola hepatica is a major pathogen of livestock
worldwide, causing huge economic losses to agriculture, as well as 2.4 million human …

Only praziquantel is available for treating schistosomiasis, a disease affecting more than
200 million people. Praziquantel-resistant worms have been selected for in the lab and low …

Thioredoxin plays a crucial role in a wide number of physiological processes, which span
from reduction of nucleotides to deoxyriboucleotides to the detoxification from xenobiotics …

Although helminth infections are characteristically associated with Th2‐mediated responses
that include the production of the prototypical cytokines IL‐4, IL‐5 and IL‐13 by CD 4+ cells …

Over the past seven decades, research on autotrophic and heterotrophic model organisms
has defined how the flow of electrons (“reducing power”) from high-energy inorganic …

Schistosomiasis is caused by parasites of the genus Schistosoma, which infect more than
200 million people. Praziquantel (PZQ) has been the main drug for controlling …

Schistosomiasis is a major neglected tropical disease. Control of schistosomiasis currently
relies on a single drug, praziquantel, and despite its efficacy against the all schistosome …

Schistosomiasis is a debilitating neglected tropical disease, caused by flatworms of
Schistosoma genus. The treatment relies on a single drug, praziquantel (PZQ), making the …