Numerical modeling of multiphase flows in microfluidics and micro process engineering: a review of methods and applications

M Wörner - Microfluidics and nanofluidics, 2012 - Springer
This article presents a comprehensive review of numerical methods and models for interface
resolving simulations of multiphase flows in microfluidics and micro process engineering …

Multiscale cancer modeling

TS Deisboeck, Z Wang, P Macklin… - Annual review of …, 2011 - annualreviews.org
Simulating cancer behavior across multiple biological scales in space and time, ie,
multiscale cancer modeling, is increasingly being recognized as a powerful tool to refine …

Nonlinear modelling of cancer: bridging the gap between cells and tumours

JS Lowengrub, HB Frieboes, F **, YL Chuang, X Li… - …, 2009 - iopscience.iop.org
Despite major scientific, medical and technological advances over the last few decades, a
cure for cancer remains elusive. The disease initiation is complex, and including initiation …

Three-dimensional multispecies nonlinear tumor growth—I: model and numerical method

SM Wise, JS Lowengrub, HB Frieboes… - Journal of theoretical …, 2008 - Elsevier
This is the first paper in a two-part series in which we develop, analyze, and simulate a
diffuse interface continuum model of multispecies tumor growth and tumor-induced …

[Књига][B] Multiscale modeling of cancer: an integrated experimental and mathematical modeling approach

V Cristini, J Lowengrub - 2010 - books.google.com
Mathematical modeling, analysis and simulation are set to play crucial roles in explaining
tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial …

A balanced force refined level set grid method for two-phase flows on unstructured flow solver grids

M Herrmann - Journal of computational physics, 2008 - Elsevier
A balanced force refined level set grid method for two-phase flows on structured and
unstructured flow solver grids is presented. To accurately track the phase interface location …

Multiscale modelling and nonlinear simulation of vascular tumour growth

P Macklin, S McDougall, ARA Anderson… - Journal of mathematical …, 2009 - Springer
In this article, we present a new multiscale mathematical model for solid tumour growth
which couples an improved model of tumour invasion with a model of tumour-induced …

The effect of interstitial pressure on tumor growth: coupling with the blood and lymphatic vascular systems

M Wu, HB Frieboes, SR McDougall… - Journal of theoretical …, 2013 - Elsevier
The flow of interstitial fluid and the associated interstitial fluid pressure (IFP) in solid tumors
and surrounding host tissues have been identified as critical elements in cancer growth and …

Nonlinear simulations of solid tumor growth using a mixture model: invasion and branching

V Cristini, X Li, JS Lowengrub, SM Wise - Journal of mathematical biology, 2009 - Springer
We develop a thermodynamically consistent mixture model for avascular solid tumor growth
which takes into account the effects of cell-to-cell adhesion, and taxis inducing chemical and …

Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): from microscopic measurements to macroscopic predictions of clinical progression

P Macklin, ME Edgerton, AM Thompson… - Journal of theoretical …, 2012 - Elsevier
Ductal carcinoma in situ (DCIS)—a significant precursor to invasive breast cancer—is
typically diagnosed as microcalcifications in mammograms. However, the effective use of …