Designing drug delivery systems for cell therapy
Cell therapies, such as immune cell and stem cell therapies, are being preclinically and
clinically explored for the treatment of various diseases, but are often limited by low efficacy …
clinically explored for the treatment of various diseases, but are often limited by low efficacy …
Nano/genetically engineered cells for immunotherapy
J Shen, Y Zhou, L Yin - BMEMat, 2024 - Wiley Online Library
Immunotherapy has recently emerged as a promising therapeutic modality for the treatment
of various diseases such as cancer, inflammation, autoimmune diseases, and infectious …
of various diseases such as cancer, inflammation, autoimmune diseases, and infectious …
Neutrophils bearing adhesive polymer micropatches as a drug-free cancer immunotherapy
Tumour-associated neutrophils can exert antitumour effects but can also assume a pro-
tumoural phenotype in the immunosuppressive tumour microenvironment. Here we show …
tumoural phenotype in the immunosuppressive tumour microenvironment. Here we show …
Micro/nano system-mediated local treatment in conjunction with immune checkpoint inhibitor against advanced-Stage malignant melanoma
L Tang, H Liu, Y Yin, T Pan, C Fu, Y Cao, Y Mei… - Chemical Engineering …, 2024 - Elsevier
Tumor relapse and metastasis become a big challenge in treating malignant melanoma
because conventional therapeutic options often fail to eradicate the tumor residue after …
because conventional therapeutic options often fail to eradicate the tumor residue after …
Backpack-mediated anti-inflammatory macrophage cell therapy for the treatment of traumatic brain injury
Traumatic brain injury (TBI) is a debilitating disease with no current therapies outside of
acute clinical management. While acute, controlled inflammation is important for debris …
acute clinical management. While acute, controlled inflammation is important for debris …
Combination of Chemical and Mechanical Tumor Immunomodulation Using Cavitating Mesoporous Silica Nanoparticles
Combinatorial methods to repolarize tumor-associated macrophages from anti-inflammatory
to pro-inflammatory phenotypes offer a promising route for cancer immunotherapy. However …
to pro-inflammatory phenotypes offer a promising route for cancer immunotherapy. However …
pH‐Sensitive Magnetic Nanoparticle‐Mediated Natural‐Killer‐Cell‐Based Microrobots for Dual‐Targeted Delivery and Induction of Pro‐Inflammatory Macrophage …
Adoptive cell therapy using natural killer (NK) cells emerges as the next‐generation cancer
immunotherapy. Based on the intrinsic capability of direct cancer cell necrosis without prior …
immunotherapy. Based on the intrinsic capability of direct cancer cell necrosis without prior …
Reprogramming Dysfunctional Dendritic Cells by a Versatile Catalytic Dual Oxide Antigen-Captured Nanosponge for Remotely Enhancing Lung Metastasis …
MR Chiang, CW Hsu, WC Pan, NT Tran, YS Lee… - ACS …, 2024 - ACS Publications
Dendritic cells (DCs) play a crucial role in initiating antitumor immune responses. However,
in the tumor environment, dendritic cells often exhibit impaired antigen presentation and …
in the tumor environment, dendritic cells often exhibit impaired antigen presentation and …
Mechanoimmune-Driven Backpack Sustains Dendritic Cell Maturation for Synergistic Tumor Radiotherapy
H Yu, Z Liu, H Guo, X Hu, Y Wang, X Cheng… - ACS …, 2024 - ACS Publications
Cell backpacks present significant potential in both therapeutic and diagnostic applications,
making it essential to further explore their interactions with host cells. Current evidence …
making it essential to further explore their interactions with host cells. Current evidence …
Dendritic Cell Immune Modulation via Polyphenol Membrane Coatings
Cellular hitchhiking is an emerging strategy for the in vivo control of adoptively transferred
immune cells. Hitchhiking approaches are primarily mediated by adhesion of nano and …
immune cells. Hitchhiking approaches are primarily mediated by adhesion of nano and …