Multicomponent syntheses of functional chromophores
L Levi, TJJ Müller - Chemical Society Reviews, 2016 - pubs.rsc.org
Multicomponent reactions are a valuable tool for the synthesis of functional π-electron
systems. Two different approaches can be taken into account for accessing the target …
systems. Two different approaches can be taken into account for accessing the target …
Metal-free domino one-pot protocols for quinoline synthesis
Quinoline is one of the most widely investigated scaffolds by synthetic chemists because of
its medicinal importance. A wide range of metal-catalyzed, metal-free, multi-step or domino …
its medicinal importance. A wide range of metal-catalyzed, metal-free, multi-step or domino …
Synthesis, spectroscopic, crystal structure, DFT, hirshfeld surface and molecular docking analysis of hexahydroquinoline derivative (HQ)
A Fatima, G Khanum, DD Agrawal… - Polycyclic Aromatic …, 2023 - Taylor & Francis
The synthesis of a HQ derivative using a one-pot multicomponent synthesis is reported.
Single crystal X-Ray diffraction at 293 K was used to characterize the material, which was …
Single crystal X-Ray diffraction at 293 K was used to characterize the material, which was …
Identification of embelin, a 3‐undecyl‐1,4‐benzoquinone from Embelia ribes as a multitargeted anti‐Alzheimer agent
Abstract Beta‐secreatse (BACE‐1) and cholinesterases are clinically validated targets of
Alzheimer's disease (AD), for which natural products have provided immense contribution …
Alzheimer's disease (AD), for which natural products have provided immense contribution …
Visible-Light-Induced Photocatalytic Aerobic Oxidative Csp3–H Functionalization of Glycine Derivatives: Synthesis of Substituted Quinolines
X Yang, L Li, Y Li, Y Zhang - The Journal of Organic Chemistry, 2016 - ACS Publications
A visible-light induced photocatalytic aerobic oxidative dehydrogenative
coupling/aromatization tandem reaction of glycine esters with unactivated alkenes has been …
coupling/aromatization tandem reaction of glycine esters with unactivated alkenes has been …
Discovery of Quinazolin-4(3H)-ones as NLRP3 Inflammasome Inhibitors: Computational Design, Metal-Free Synthesis, and in Vitro Biological Evaluation
NLRP3 inflammasome is an important therapeutic target for a number of human diseases.
Herein, computationally designed series of quinazolin-4 (3 H)-ones were synthesized using …
Herein, computationally designed series of quinazolin-4 (3 H)-ones were synthesized using …
Transition-metal-free approach for the synthesis of 4-aryl-quinolines from alkynes and anilines
M Phanindrudu, SB Wakade, DK Tiwari… - The Journal of …, 2018 - ACS Publications
An efficient and transition-metal-free approach for the synthesis of 4-arylquinolines from
readily available anilines and alkynes in the presence of K2S2O8 and DMSO has been …
readily available anilines and alkynes in the presence of K2S2O8 and DMSO has been …
Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure–activity relationship
The screening of IIIM natural products repository for P-gp modulatory activity in P-gp over-
expressing human adenocarcinoma LS-180 cells led to the identification of 7 natural …
expressing human adenocarcinoma LS-180 cells led to the identification of 7 natural …
Ten years of progress in the synthesis of six-membered N-heterocycles from alkynes and nitrogen sources
JSS Neto, G Zeni - Tetrahedron, 2020 - Elsevier
The purpose of this review is to highlight ten years of success in the synthesis of six-
membered N-heterocycles using alkynes and nitrogen sources as substrates. It is our hope …
membered N-heterocycles using alkynes and nitrogen sources as substrates. It is our hope …
Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors
Alkaloids have always been a great source of cholinesterase inhibitors. Numerous studies
have shown that inhibiting acetylcholinesterase as well as butyrylcholinetserase is …
have shown that inhibiting acetylcholinesterase as well as butyrylcholinetserase is …