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[HTML][HTML] Effects of polycyclic aromatic hydrocarbons (PAHs) on pregnancy, placenta, and placental trophoblasts
Polycyclic aromatic hydrocarbons (PAHs) are a group of persistent organic pollutants that
are carcinogenic, mutagenic, endocrine-toxic, and immunotoxic. PAHs can be found in …
are carcinogenic, mutagenic, endocrine-toxic, and immunotoxic. PAHs can be found in …
Spontaneous preterm birth: Involvement of multiple feto-maternal tissues and organ systems, differing mechanisms, and pathways
Survivors of preterm birth struggle with multitudes of disabilities due to improper in utero
programming of various tissues and organ systems contributing to adult-onset diseases at a …
programming of various tissues and organ systems contributing to adult-onset diseases at a …
circRNA mediates silica-induced macrophage activation via HECTD1/ZC3H12A-dependent ubiquitination
Z Zhou, R Jiang, X Yang, H Guo, S Fang… - …, 2018 - pmc.ncbi.nlm.nih.gov
Rationale: Phagocytosis of silicon dioxide (SiO2) into lung cells causes an inflammatory
cascade that results in fibroblast proliferation and migration, followed by fibrosis. Circular …
cascade that results in fibroblast proliferation and migration, followed by fibrosis. Circular …
BCL6, a key oncogene, in the placenta, pre-eclampsia and endometriosis
BACKGROUND The key oncogene B-cell lymphoma 6 (BCL6) drives malignant progression
by promoting proliferation, overriding DNA damage checkpoints and blocking cell terminal …
by promoting proliferation, overriding DNA damage checkpoints and blocking cell terminal …
Zika virus causes placental pyroptosis and associated adverse fetal outcomes by activating GSDME
Z Zhao, Q Li, U Ashraf, M Yang, W Zhu, J Gu, Z Chen… - Elife, 2022 - elifesciences.org
Zika virus (ZIKV) can be transmitted from mother to fetus during pregnancy, causing adverse
fetal outcomes. Several studies have indicated that ZIKV can damage the fetal brain directly; …
fetal outcomes. Several studies have indicated that ZIKV can damage the fetal brain directly; …
Progesterone-mediated remodeling of the maternal-fetal interface by a PGRMC1-dependent mechanism
Implantation and maintenance of pregnancy involve intricate immunological processes that
enable the develo** fetus to coexist with the maternal immune system. Progesterone, a …
enable the develo** fetus to coexist with the maternal immune system. Progesterone, a …
Co-culture of JEG-3, BeWo and syncBeWo cell lines with adrenal H295R cell line: an alternative model for examining endocrine and metabolic properties of the …
E Drwal, A Rak, E Gregoraszczuk - Cytotechnology, 2018 - Springer
Monocultures of different placental cells are used for many physiological and toxicological
studies; however, they are not a true reflection of the interaction between placenta and fetus …
studies; however, they are not a true reflection of the interaction between placenta and fetus …
Endometrial changes in estrogen and progesterone receptor expression during implantation in an oocyte donation program
Implantation is the final and most important stage of embryogenesis and is of paramount
importance in achieving a successful pregnancy. Progesterone and estrogen are steroid …
importance in achieving a successful pregnancy. Progesterone and estrogen are steroid …
Involvement of the endocrine-disrupting chemical bisphenol A (BPA) in human placentation
SC de Aguiar Greca, I Kyrou, R Pink… - Journal of clinical …, 2020 - mdpi.com
Background: Endocrine-disrupting chemicals (EDCs) are environmental chemicals/toxicants
that humans are exposed to, interfering with the action of multiple hormones. Bisphenol A …
that humans are exposed to, interfering with the action of multiple hormones. Bisphenol A …
Plasminogen activator inhibitor 1 RNA-binding protein interacts with progesterone receptor membrane component 1 to regulate progesterone's ability to maintain the …
JJ Peluso, A Yuan, X Liu, V Lodde - Biology of reproduction, 2013 - academic.oup.com
Progesterone receptor membrane component 1 (PGRMC1) mediates the antiapoptotic
action of progesterone (P4). PGRMC1 interacts with plasminogen activator inhibitor 1 RNA …
action of progesterone (P4). PGRMC1 interacts with plasminogen activator inhibitor 1 RNA …