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The amyloid-β pathway in Alzheimer's disease
Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …
center of Alzheimer's disease (AD) pathophysiology. While the detailed molecular …
Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insight
Neurodegenerative diseases are the most common cause of dementia. Although their
underlying molecular pathologies have been identified, there is substantial heterogeneity in …
underlying molecular pathologies have been identified, there is substantial heterogeneity in …
Seeing beyond the brain: Conditional diffusion model with sparse masked modeling for vision decoding
Decoding visual stimuli from brain recordings aims to deepen our understanding of the
human visual system and build a solid foundation for bridging human and computer vision …
human visual system and build a solid foundation for bridging human and computer vision …
[HTML][HTML] Anterior insula as a gatekeeper of executive control
Executive control is a complex high-level cognitive function that relies on distributed brain
circuitry. We propose that the anterior insular cortex plays an under-appreciated role in …
circuitry. We propose that the anterior insular cortex plays an under-appreciated role in …
The salience network: a neural system for perceiving and responding to homeostatic demands
WW Seeley - Journal of Neuroscience, 2019 - jneurosci.org
The term “salience network” refers to a suite of brain regions whose cortical hubs are the
anterior cingulate and ventral anterior insular (ie, frontoinsular) cortices. This network, which …
anterior cingulate and ventral anterior insular (ie, frontoinsular) cortices. This network, which …
The self in context: brain systems linking mental and physical health
Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …
systems that jointly regulate somatic physiology and high-level cognition. Key systems …
The neuropathological diagnosis of Alzheimer's disease
MA DeTure, DW Dickson - Molecular neurodegeneration, 2019 - Springer
Alzheimer's disease is a progressive neurodegenerative disease most often associated with
memory deficits and cognitive decline, although less common clinical presentations are …
memory deficits and cognitive decline, although less common clinical presentations are …
Single subject prediction of brain disorders in neuroimaging: Promises and pitfalls
Neuroimaging-based single subject prediction of brain disorders has gained increasing
attention in recent years. Using a variety of neuroimaging modalities such as structural …
attention in recent years. Using a variety of neuroimaging modalities such as structural …
Current and future directions of deep brain stimulation for neurological and psychiatric disorders: JNSPG 75th Anniversary Invited Review Article
Deep brain stimulation (DBS) has evolved considerably over the past 4 decades. Although it
has primarily been used to treat movement disorders such as Parkinson's disease, essential …
has primarily been used to treat movement disorders such as Parkinson's disease, essential …
Salience processing and insular cortical function and dysfunction
LQ Uddin - Nature reviews neuroscience, 2015 - nature.com
The brain is constantly bombarded by stimuli, and the relative salience of these inputs
determines which are more likely to capture attention. A brain system known as the'salience …
determines which are more likely to capture attention. A brain system known as the'salience …