Metal complex catalysis in the synthesis of spirocarbocycles

VA D'yakonov, OA Trapeznikova, A de Meijere… - Chemical …, 2014 - ACS Publications
Spirans contain at least two rings, which share one carbon atom called the spirocarbon
atom. 1 Synthetic and natural spirocarbocycles attract the attention of organic chemists due …

[HTML][HTML] Recent advances in transition-metal-catalyzed intermolecular carbomagnesiation and carbozincation

K Murakami, H Yorimitsu - Beilstein journal of organic …, 2013 - beilstein-journals.org
Carbomagnesiation and carbozincation reactions are efficient and direct routes to prepare
complex and stereodefined organomagnesium and organozinc reagents. However, carbon …

The facile synthesis of the 5Z, 9Z-dienoic acids and their topoisomerase I inhibitory activity

VA D'yakonov, AA Makarov, LU Dzhemileva… - Chemical …, 2013 - pubs.rsc.org
An original, effective approach to the synthesis of natural and synthetic 5Z, 9Z-dienoic acids
in high yields (61–67%) and with high selectivity (> 98%) was developed. The approach is …

Advances in the chemistry of natural and semisynthetic topoisomerase I/II inhibitors

VA D'yakonov, LU Dzhemileva… - Studies in natural products …, 2017 - Elsevier
The search for new, effective, and low-toxic anticancer agents is one of the most important
tasks of modern medicinal chemistry. In general, the solution to this problem comes down to …

Metallacomplex catalysis in the synthesis of regular isoprenoids

UM Dzhemilev, LU Dzhemileva… - Russian Chemical Bulletin, 2023 - Springer
This brief review covers and systematizes the key results acquired using metal complex
catalysts in both fundamental and applied research aimed at the development of methods …

Natural compounds with bis-methylene-interrupted Z-double bonds: plant sources, strategies of total synthesis, biological activity, and perspectives

VA D'yakonov, LU Dzhemileva, UM Dzhemilev - Phytochemistry Reviews, 2021 - Springer
The review summarizes data on natural compounds including higher carboxylic acids,
acetogenins, lembehynes, and insect pheromones containing bis-methylene-interrupted Z …

Natural Acetogenins, Chatenaytrienins-1,-2,-3 and-4, Mitochondrial Potential Uncouplers and Autophagy Inducers—Promising Anticancer Agents

LU Dzhemileva, RA Tuktarova, UM Dzhemilev… - Antioxidants, 2023 - mdpi.com
The present paper details the complete stereoselective synthesis of four natural
acetogenins, chatenaytrienins-1,-2,-3 and-4, previously isolated from the roots of fruit trees …

nZ,(n + 4)Z-Dienoic fatty acids: a new method for the synthesis and inhibitory action on topoisomerase I and IIα

VA D'yakonov, LU Dzhemileva, AA Makarov… - Medicinal Chemistry …, 2016 - Springer
An original, effective approach to the stereoselective method for the synthesis of higher
unsaturated acids containing a 1Z, 5Z-diene group in 61–75% yields and with> 98 …

Novel organomagnesium reagents in synthesis. Catalytic cyclomagnesiation of allenes in the synthesis of N-, O-, and Si-substituted 1Z, 5Z-dienes

VA D'yakonov, AA Makarov, EK Makarova… - Tetrahedron, 2013 - Elsevier
An efficient method for the synthesis of valuable N-, O-, and Si-containing 1Z, 5Z-diene
compounds was developed. The method comprises Cp 2 TiCl 2-catalyzed homo-and cross …

Catalytic cyclometalation reaction of unsaturated compounds in synthesis of magnesa-and aluminacarbocycles

UM Dzhemilev, AG Ibragimov - Journal of Organometallic Chemistry, 2010 - Elsevier
The investigation results on design and application of the new catalytic cyclometalation
reaction of olefins, dienes, acetylenes and allenes with Al, Mg and halogen alkyls mediated …