Radioprotection and radiomitigation: from the bench to clinical practice

E Obrador, R Salvador, JI Villaescusa, JM Soriano… - Biomedicines, 2020 - mdpi.com
The development of protective agents against harmful radiations has been a subject of
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …

Sesamol, a major lignan in sesame seeds (Sesamum indicum): Anti-cancer properties and mechanisms of action

AF Majdalawieh, ZR Mansour - European journal of pharmacology, 2019 - Elsevier
Sesamol is a natural phenolic compound and a major lignan isolated from sesame seeds
(Sesamum indicum) and sesame oil. The therapeutic potential of sesamol was investigated …

Nuclear and radiological emergencies: biological effects, countermeasures and biodosimetry

E Obrador, R Salvador-Palmer, JI Villaescusa… - Antioxidants, 2022 - mdpi.com
Atomic and radiological crises can be caused by accidents, military activities, terrorist
assaults involving atomic installations, the explosion of nuclear devices, or the utilization of …

Sesamol supplementation attenuates DSS-induced colitis via mediating gut barrier integrity, inflammatory responses, and resha** gut microbiome

B Zhao, B **a, X Li, L Zhang, X Liu, R Shi… - Journal of Agricultural …, 2020 - ACS Publications
Sesamol, a liposoluble lignan extract, has already been proved to possess potent anti-
inflammatory properties, and it could also regulate gut dysfunction. The purpose of the …

Pharmacology of natural radioprotectors

GI Mun, S Kim, E Choi, CS Kim, YS Lee - Archives of pharmacal research, 2018 - Springer
Radiotherapy is one of the most efficient ways to treat cancer. However, deleterious effects,
such as acute and chronic toxicities that reduce the quality of life, may result. Naturally …

Radiation protection and mitigation by natural antioxidants and flavonoids: implications to radiotherapy and radiation disasters

R Yahyapour, D Shabeeb, M Cheki… - Current molecular …, 2018 - ingentaconnect.com
Background: Nowadays, ionizing radiations are used for various medical and terroristic
aims. These purposes involve exposure to ionizing radiations. Hence, people are at risk for …

Phytochemicals: A potential next generation agent for radioprotection

BP Jit, S Pattnaik, R Arya, R Dash, SS Sahoo… - Phytomedicine, 2022 - Elsevier
Background Radiation hazards are accountable for extensive damage in the biological
system and acts as a public health burden. Owing to the rapid increasing in radiation …

Radiotherapy-induced digestive injury: diagnosis, treatment and mechanisms

G Chen, Y Han, H Zhang, W Tu, S Zhang - Frontiers in oncology, 2021 - frontiersin.org
Radiotherapy is one of the main therapeutic methods for treating cancer. The digestive
system consists of the gastrointestinal tract and the accessory organs of digestion (the …

Resveratrol as an enhancer of apoptosis in cancer: a mechanistic review

M Ashrafizadeh, S Taeb… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
The resistance to therapy of cancer cells is a challenge for achieving an appropriate
therapeutic outcome. Cancer (stem) cells possess several mechanisms for increasing their …

Protective effects of sesamol on systemic inflammation and cognitive impairment in aging mice

B Ren, T Yuan, X Zhang, L Wang, J Pan… - Journal of agricultural …, 2020 - ACS Publications
Sesamol, a lignan in sesame, possesses several bioactivities, such as antioxidation, anti-
inflammation, and neuroprotective capability. In this study, the effects of sesamol on aging …