Recent advances in the treatment of melanoma

BD Curti, MB Faries - New England Journal of Medicine, 2021 - Mass Medical Soc
Advances in Melanoma Treatment The incidence of melanoma has increased, but mortality
has declined with improved management. Sentinel-node sampling has reduced morbidity …

NCCN Guidelines® insights: melanoma: cutaneous, version 2.2021: featured updates to the NCCN guidelines

SM Swetter, JA Thompson, MR Albertini… - Journal of the National …, 2021 - jnccn.org
Over the past few years, the NCCN Guidelines for Melanoma: Cutaneous have been
expanded to include pathways for treatment of microscopic satellitosis (added in v2. 2020) …

Molecular biomarkers for melanoma screening, diagnosis and prognosis: current state and future prospects

DC Deacon, EA Smith, RL Judson-Torres - Frontiers in Medicine, 2021 - frontiersin.org
Despite significant progress in the development of treatment options, melanoma remains a
leading cause of death due to skin cancer. Advances in our understanding of the genetic …

[HTML][HTML] An epidemiologic analysis of melanoma overdiagnosis in the United States, 1975–2017

NR Kurtansky, SW Dusza, AC Halpern… - Journal of Investigative …, 2022 - Elsevier
The primary cause of the increase in melanoma incidence in the United States has been
suggested to be overdiagnosis. We used Surveillance, Epidemiology, and End Result …

Cutaneous melanoma: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

T Amaral, M Ottaviano, A Arance, C Blank… - Annals of …, 2025 - Elsevier
This European Society for Medical Oncology (ESMO) Clinical Practice Guideline (CPG)
focuses on invasive cutaneous melanoma. The management of uveal melanoma and non …

Expert consensus on the use of prognostic gene expression profiling tests for the management of cutaneous melanoma: consensus from the skin cancer prevention …

AS Farberg, JW Marson, A Glazer, GH Litchman… - Dermatology and …, 2022 - Springer
Background Prognostic assessment of cutaneous melanoma relies on historical,
clinicopathological, and phenotypic risk factors according to American Joint Committee on …

Nodular Melanoma

C Gronbeck, PE Kerr - Clinics in Dermatology, 2025 - Elsevier
Nodular melanoma (NM) is the second most common subtype of cutaneous melanoma
(CM), accounting for a substantial proportion of melanoma fatalities. We assessed reviews …

[HTML][HTML] The Use of Single-Cell RNA-Sequencing and Spatial Transcriptomics in Understanding the Pathogenesis and Treatment of Skin Diseases

AE Houser, A Kazmi, AK Nair, AL Ji - JID Innovations, 2023 - Elsevier
The development of multiomic profiling tools has rapidly expanded in recent years, along
with their use in profiling skin tissues in various contexts, including dermatologic diseases …

Using a clinicopathologic and gene expression (CP-GEP) model to identify stage I–II melanoma patients at risk of disease relapse

EEAP Mulder, I Johansson, DJ Grünhagen, D Tempel… - Cancers, 2022 - mdpi.com
Simple Summary More than 40% of patients initially diagnosed with 'low risk'(stage I–II)
melanoma eventually develop melanoma recurrence or die as a result of melanoma. While …

Advances in melanoma: Epidemiology, diagnosis, and prognosis

S Waseh, JB Lee - Frontiers in Medicine, 2023 - frontiersin.org
Unraveling the multidimensional complexities of melanoma has required concerted efforts
by dedicated community of researchers and clinicians battling against this deadly form of …