New advances in separation science for metabolomics: resolving chemical diversity in a post-genomic era
NL Kuehnbaum, P Britz-McKibbin - Chemical reviews, 2013 - ACS Publications
Metabolomics offers a revolutionary framework for phenoty** individuals at a molecular
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …
Current metabolomics: technological advances
Metabolomics, the global quantitative assessment of metabolites in a biological system, has
played a pivotal role in various fields of science in the post-genomic era. Metabolites are the …
played a pivotal role in various fields of science in the post-genomic era. Metabolites are the …
Titin-truncating variants affect heart function in disease cohorts and the general population
Titin-truncating variants (TTNtv) commonly cause dilated cardiomyopathy (DCM). TTNtv are
also encountered in∼ 1% of the general population, where they may be silent, perhaps …
also encountered in∼ 1% of the general population, where they may be silent, perhaps …
Bioinformatics tools for mass spectroscopy-based metabolomic data processing and analysis
Biological systems are increasingly being studied in a holistic manner, using omics
approaches, to provide quantitative and qualitative descriptions of the diverse collection of …
approaches, to provide quantitative and qualitative descriptions of the diverse collection of …
[HTML][HTML] Next-generation capillary electrophoresis–mass spectrometry approaches in metabolomics
Highlights•CE–MS is an attractive analytical tool for analyzing the polar ionogenic
metabolome.•A novel sheathless interface for CE–MS allows highly sensitive metabolic …
metabolome.•A novel sheathless interface for CE–MS allows highly sensitive metabolic …
Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles
Chronic fatigue syndrome (CFS) is a persistent and unexplained pathological state
characterized by exertional and severely debilitating fatigue, with/without infectious or …
characterized by exertional and severely debilitating fatigue, with/without infectious or …
Autophagy contributes to nighttime energy availability for growth in Arabidopsis
Autophagy is an intracellular process leading to the vacuolar degradation of cytoplasmic
components. Autophagic degradation of chloroplasts is particularly activated in leaves under …
components. Autophagic degradation of chloroplasts is particularly activated in leaves under …
[HTML][HTML] Analytical challenges and solutions for performing metabolomic analysis of root exudates
ME Casas, V Matamoros - Trends in Environmental Analytical Chemistry, 2021 - Elsevier
Plant stress responses are mediated by the release of chemical compounds called exudates
into the rhizosphere. These chemical substances include primary and secondary plant …
into the rhizosphere. These chemical substances include primary and secondary plant …
Metabolomics, peptidomics and proteomics applications of capillary electrophoresis-mass spectrometry in Foodomics: a review
C Ibáñez, C Simó, V García-Cañas, A Cifuentes… - Analytica chimica …, 2013 - Elsevier
In the current post-genomic era, Foodomics has been defined as a discipline that studies
food and nutrition through the application of advanced omics approaches. Foodomics …
food and nutrition through the application of advanced omics approaches. Foodomics …
Metabolome analysis based on capillary electrophoresis-mass spectrometry
A Hirayama, M Wakayama, T Soga - TrAC Trends in Analytical Chemistry, 2014 - Elsevier
Capillary electrophoresis-mass spectrometry (CE-MS) has emerged as a powerful new tool
for comprehensive analysis of charged compounds. In this review, we provide a general …
for comprehensive analysis of charged compounds. In this review, we provide a general …