New advances in separation science for metabolomics: resolving chemical diversity in a post-genomic era

NL Kuehnbaum, P Britz-McKibbin - Chemical reviews, 2013 - ACS Publications
Metabolomics offers a revolutionary framework for phenoty** individuals at a molecular
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …

Current metabolomics: technological advances

SP Putri, S Yamamoto, H Tsugawa… - Journal of bioscience and …, 2013 - Elsevier
Metabolomics, the global quantitative assessment of metabolites in a biological system, has
played a pivotal role in various fields of science in the post-genomic era. Metabolites are the …

Titin-truncating variants affect heart function in disease cohorts and the general population

S Schafer, A De Marvao, E Adami, LR Fiedler, B Ng… - Nature …, 2017 - nature.com
Titin-truncating variants (TTNtv) commonly cause dilated cardiomyopathy (DCM). TTNtv are
also encountered in∼ 1% of the general population, where they may be silent, perhaps …

Bioinformatics tools for mass spectroscopy-based metabolomic data processing and analysis

M Sugimoto, M Kawakami, M Robert… - Current …, 2012 - ingentaconnect.com
Biological systems are increasingly being studied in a holistic manner, using omics
approaches, to provide quantitative and qualitative descriptions of the diverse collection of …

[HTML][HTML] Next-generation capillary electrophoresis–mass spectrometry approaches in metabolomics

W Zhang, T Hankemeier, R Ramautar - Current opinion in biotechnology, 2017 - Elsevier
Highlights•CE–MS is an attractive analytical tool for analyzing the polar ionogenic
metabolome.•A novel sheathless interface for CE–MS allows highly sensitive metabolic …

Index markers of chronic fatigue syndrome with dysfunction of TCA and urea cycles

E Yamano, M Sugimoto, A Hirayama, S Kume… - Scientific reports, 2016 - nature.com
Chronic fatigue syndrome (CFS) is a persistent and unexplained pathological state
characterized by exertional and severely debilitating fatigue, with/without infectious or …

Autophagy contributes to nighttime energy availability for growth in Arabidopsis

M Izumi, J Hidema, A Makino, H Ishida - Plant physiology, 2013 - academic.oup.com
Autophagy is an intracellular process leading to the vacuolar degradation of cytoplasmic
components. Autophagic degradation of chloroplasts is particularly activated in leaves under …

[HTML][HTML] Analytical challenges and solutions for performing metabolomic analysis of root exudates

ME Casas, V Matamoros - Trends in Environmental Analytical Chemistry, 2021 - Elsevier
Plant stress responses are mediated by the release of chemical compounds called exudates
into the rhizosphere. These chemical substances include primary and secondary plant …

Metabolomics, peptidomics and proteomics applications of capillary electrophoresis-mass spectrometry in Foodomics: a review

C Ibáñez, C Simó, V García-Cañas, A Cifuentes… - Analytica chimica …, 2013 - Elsevier
In the current post-genomic era, Foodomics has been defined as a discipline that studies
food and nutrition through the application of advanced omics approaches. Foodomics …

Metabolome analysis based on capillary electrophoresis-mass spectrometry

A Hirayama, M Wakayama, T Soga - TrAC Trends in Analytical Chemistry, 2014 - Elsevier
Capillary electrophoresis-mass spectrometry (CE-MS) has emerged as a powerful new tool
for comprehensive analysis of charged compounds. In this review, we provide a general …