Review of the recombinant human interferon gamma as an immunotherapeutic: Impacts of production platforms and glycosylation

A Razaghi, L Owens, K Heimann - Journal of biotechnology, 2016 - Elsevier
Human interferon gamma is a cytokine belonging to a diverse group of interferons which
have a crucial immunological function against mycobacteria and a wide variety of viral …

Production and Purification of Recombinant Proteins from Escherichia coli

NK Tripathi - ChemBioEng Reviews, 2016 - Wiley Online Library
Abstract Development of successful production strategies for recombinant proteins is a
challenging task due to problems associated with the scale‐up of bioprocesses. Recent …

Increasing recombinant protein production in Escherichia coli through metabolic and genetic engineering

H Waegeman, W Soetaert - Journal of Industrial Microbiology …, 2011 - academic.oup.com
Different hosts have been used for recombinant protein production, ranging from simple
bacteria, such as Escherichia coli and Bacillus subtilis, to more advanced eukaryotes as …

Production of recombinant scorpion antivenoms in E. coli: current state and perspectives

SM Alonso Villela, H Kraïem-Ghezal… - Applied Microbiology …, 2023 - Springer
Scorpion envenomation is a serious health problem in tropical and subtropical zones. The
access to scorpion antivenom is sometimes limited in availability and specificity. The …

Development of nsP2 protease based cell free high throughput screening assay for evaluation of inhibitors against emerging Chikungunya virus

A Saha, BN Acharya, R Priya, NK Tripathi… - Scientific reports, 2018 - nature.com
Chikungunya virus has emerged as one of the most important global arboviral threats over
the last decade. Inspite of large scale morbidity, with long lasting polyarthralgia, so far no …

Development of multispecies recombinant nucleoprotein-based indirect ELISA for high-throughput screening of Crimean-Congo hemorrhagic fever virus-specific …

N Shrivastava, A Shrivastava, SM Ninawe… - Frontiers in …, 2019 - frontiersin.org
Crimean-Congo hemorrhagic fever (CCHF) is a re-emerging zoonotic viral disease
prevalent in many parts of Asia, Europe, and Africa. The causative agent, Crimean-Congo …

Enhanced production of insulin-like growth factor I protein in Escherichia coli by optimization of five key factors

J Ranjbari, V Babaeipour, H Vahidi… - Iranian Journal of …, 2015 - pmc.ncbi.nlm.nih.gov
Human insulin-like growth factor I (hIGF-I) is a kind of growth factor with clinical significance
in medicine. Up to now, E. coli expression system has been widely used as a host to …

Optimization of medium composition to increase the expression of recombinant human interferon-β using the Plackett–Burman and central composite design in E. coli …

D Pal, G Patel, P Dobariya, SH Nile, AH Pande… - 3 Biotech, 2021 - Springer
Recombinant human interferon-β (rhIFN-β) is therapeutically important and new
commercially viable approaches are needed for its increased production. In this study, a …

Expression and production of recombinant scorpine as a potassium channel blocker protein in Escherichia coli

R Seyfi, V Babaeipour, MR Mofid… - Biotechnology and …, 2019 - Wiley Online Library
Scorpine is a cationic protein from the venom of Pandinus imperator, belonging to potassium
channel blocker family, which has been shown to have antibacterial, antiviral, and …

An improved method for high-level soluble expression and purification of recombinant amyloid-beta peptide for in vitro studies

G Chhetri, T Pandey, R Chinta, A Kumar… - Protein Expression and …, 2015 - Elsevier
Amyloid-beta (Aβ) peptide mediates several neurodegenerative diseases. The 42 amino
acid (Aβ 1–42) is the predominant form of peptide found in the neuritic plaques and has …