2024 ESC Guidelines for the management of elevated blood pressure and hypertension: Developed by the task force on the management of elevated blood pressure …

JW McEvoy, CP McCarthy, RM Bruno… - European heart …, 2024 - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Molecular mechanisms linking osteoarthritis and Alzheimer's disease: shared pathways, mechanisms and breakthrough prospects

IO Umoh, HJ Dos Reis, ACP de Oliveira - International Journal of …, 2024 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease mostly affecting the
elderly population. It is characterized by cognitive decline that occurs due to impaired …

A heart-healthy and stroke-free world: using data to inform global action

GA Mensah, V Fuster, GA Roth - Journal of the American College of …, 2023 - jacc.org
An important update has been made to the estimation of the prevalence of YLD due to IHD.
Previously, the prevalence of IHD represented the aggregate of 3 separately estimated IHD …

Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition

F Eichelmann, M Prada, L Sellem, KG Jackson… - Nature Medicine, 2024 - nature.com
Current cardiometabolic disease prevention guidelines recommend increasing dietary
unsaturated fat intake while reducing saturated fats. Here we use lipidomics data from a …

[HTML][HTML] Obicetrapib on top of maximally tolerated lipid‐modifying therapies in participants with or at high risk for atherosclerotic cardiovascular disease: rationale and …

SJ Nicholls, AJ Nelson, M Ditmarsch, JJP Kastelein… - American heart …, 2024 - Elsevier
Background Obicetrapib, a novel, selective cholesteryl ester transfer protein (CETP)
inhibitor, reduces low-density lipoprotein cholesterol (LDL-C), LDL particles, apolipoprotein …

Personalized Intervention Based on Early Detection of Atherosclerosis: JACC State-of-the-Art Review

RV Nielsen, V Fuster, H Bundgaard, JJ Fuster… - Journal of the American …, 2024 - jacc.org
Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality
worldwide and challenges the capacity of health care systems globally. Atherosclerosis is …

[HTML][HTML] Effects of long-term exposure to ambient fine particulate matter and its specific components on blood pressure and hypertension incidence

L Fu, Y Guo, Q Zhu, Z Chen, S Yu, J Xu, W Tang… - Environment …, 2024 - Elsevier
Background Epidemiological evidence on the association of PM 2.5 (particulate matter with
aerodynamic diameter≤ 2.5 μm) and its specific components with hypertension and blood …

Effects of glucagon-like peptide 1 receptor agonists on atrial fibrillation recurrence after catheter ablation: A systematic review and meta-analysis

P Karakasis, N Fragakis, D Patoulias, P Theofilis… - Advances in …, 2024 - Springer
Introduction Despite the technological advancements in catheter ablation strategies, the
recurrence of atrial fibrillation (AF) post-ablation remains a concern that requires further …

Association between triglyceride glucose-waist height ratio index and cardiovascular disease in middle-aged and older Chinese individuals: a nationwide cohort study

Q Ren, Y Huang, Q Liu, T Chu, G Li, Z Wu - Cardiovascular Diabetology, 2024 - Springer
Abstract Background The triglyceride-glucose (TyG) index and its combination with obesity
indicators can predict cardiovascular diseases (CVD). However, there is limited research on …

Risk estimation for the primary prevention of cardiovascular disease: considerations for appropriate risk prediction model selection

KR van Daalen, D Zhang, S Kaptoge… - The Lancet Global …, 2024 - thelancet.com
Cardiovascular diseases remain the number one cause of death globally. Cardiovascular
disease risk scores are an integral tool in primary prevention, being used to identify …