Recent trends in biocatalysis

D Yi, T Bayer, CPS Badenhorst, S Wu… - Chemical Society …, 2021‏ - pubs.rsc.org
Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …

Transcription-factor-based biosensor engineering for applications in synthetic biology

N Ding, S Zhou, Y Deng - ACS Synthetic Biology, 2021‏ - ACS Publications
Transcription-factor-based biosensors (TFBs) are often used for metabolite detection,
adaptive evolution, and metabolic flux control. However, designing TFBs with superior …

Diversity, versatility and complexity of bacterial gene regulation mechanisms: opportunities and drawbacks for applications in synthetic biology

I Bervoets, D Charlier - FEMS microbiology reviews, 2019‏ - academic.oup.com
Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …

Transcription factor-based biosensor: A molecular-guided approach for advanced biofuel synthesis

M Lu, Y Sha, V Kumar, Z Xu, R Zhai, M ** - Biotechnology advances, 2024‏ - Elsevier
As a sustainable and renewable alternative to petroleum fuels, advanced biofuels shoulder
the responsibility of energy saving, emission reduction and environmental protection …

Genetic biosensor design for natural product biosynthesis in microorganisms

GS Hossain, M Saini, R Miyake, H Ling… - Trends in …, 2020‏ - cell.com
Low yield and low titer of natural products are common issues in natural product
biosynthesis through microbial cell factories. One effective way to resolve such bottlenecks …

Fundamental design principles for transcription-factor-based metabolite biosensors

AA Mannan, D Liu, F Zhang, DA Oyarzún - ACS synthetic biology, 2017‏ - ACS Publications
Metabolite biosensors are central to current efforts toward precision engineering of
metabolism. Although most research has focused on building new biosensors, their …

Transcription factor-based biosensors: a molecular-guided approach for natural product engineering

MM Mitchler, JM Garcia, NE Montero… - Current opinion in …, 2021‏ - Elsevier
Natural products and their derivatives offer a rich source of chemical and biological diversity;
however, traditional engineering of their biosynthetic pathways to improve yields and access …

Transcription factor-based biosensors for screening and dynamic regulation

J Tellechea-Luzardo, MT Stiebritz… - … in bioengineering and …, 2023‏ - frontiersin.org
Advances in synthetic biology and genetic engineering are bringing into the spotlight a wide
range of bio-based applications that demand better sensing and control of biological …

A progesterone biosensor derived from microbial screening

C Grazon, RC Baer, U Kuzmanović, T Nguyen… - Nature …, 2020‏ - nature.com
Bacteria are an enormous and largely untapped reservoir of biosensing proteins. We
describe an approach to identify and isolate bacterial allosteric transcription factors (aTFs) …

Translating new synthetic biology advances for biosensing into the earth and environmental sciences

I Del Valle, EM Fulk, P Kalvapalle, JJ Silberg… - Frontiers in …, 2021‏ - frontiersin.org
The rapid diversification of synthetic biology tools holds promise in making some classically
hard-to-solve environmental problems tractable. Here we review longstanding problems in …