Pathophysiology, prevention, and treatment of medication overuse headache

HC Diener, D Dodick, S Evers, D Holle… - The Lancet …, 2019‏ - thelancet.com
Regular or frequent use of analgesics and acute antimigraine drugs can increase the
frequency of headache, and induce the transition from episodic to chronic headache or …

Medication-overuse headache: a widely recognized entity amidst ongoing debate

N Vandenbussche, D Laterza, M Lisicki, J Lloyd… - The journal of headache …, 2018‏ - Springer
Medication overuse in primary headache disorders is a worldwide phenomenon and has a
role in the chronification of headache disorders. The burden of disease on individuals and …

Effect of ubrogepant vs placebo on pain and the most bothersome associated symptom in the acute treatment of migraine: the ACHIEVE II randomized clinical trial

RB Lipton, DW Dodick, J Ailani, K Lu, M Finnegan… - Jama, 2019‏ - jamanetwork.com
Importance Ubrogepant is an oral calcitonin gene–related peptide receptor antagonist under
investigation for acute treatment of migraine. Objective To evaluate the efficacy and …

Guidelines of the International Headache Society for controlled trials of preventive treatment of migraine attacks in episodic migraine in adults

HC Diener, C Tassorelli, DW Dodick… - …, 2020‏ - journals.sagepub.com
Clinical trials are a key component of the evidence base for the treatment of headache
disorders. In 1991, the International Headache Society Clinical Trials Standing Committee …

Migraine and tension-type headache: diagnosis and treatment

R Burch - Medical Clinics, 2019‏ - medical.theclinics.com
Migraine is a recurrent, often disabling headache with neurovascular pathophysiology. It is
highly prevalent in the United States and around the world, affecting an estimated 37 million …

The impact of spinal manipulation on migraine pain and disability: a systematic review and meta‐analysis

PM Rist, A Hernandez, C Bernstein… - … : The Journal of …, 2019‏ - Wiley Online Library
Background Several small studies have suggested that spinal manipulation may be an
effective treatment for reducing migraine pain and disability. We performed a systematic …

[HTML][HTML] Antagonism of CGRP receptor: central and peripheral mechanisms and mediators in an animal model of chronic migraine

R Greco, C Demartini, M Francavilla, AM Zanaboni… - Cells, 2022‏ - mdpi.com
Calcitonin-gene-related peptide (CGRP) plays a key role in migraine pathophysiology and
more specifically in the mechanisms underlying peripheral and central sensitization. Here …

Questionnaire-based survey on the prevalence of medication-overuse headache in Japanese one city—Itoigawa study

M Katsuki, C Yamagishi, Y Matsumori, A Koh… - Neurological …, 2022‏ - Springer
Objective The medication-overuse headache (MOH) prevalence has not been investigated
in a general Japanese population. We performed questionnaire-based survey and revealed …

Management of medication overuse (MO) and medication overuse headache (MOH) S1 guideline

HC Diener, P Kropp, T Dresler, S Evers… - … research and practice, 2022‏ - Springer
Introduction Chronic headache due to the overuse of medication for the treatment of
migraine attacks has a prevalence of 0.5–2.0%. This guideline provides guidance for the …

A real‐world analysis of migraine: A cross‐sectional study of disease burden and treatment patterns

JH Ford, J Jackson, G Milligan, S Cotton… - … : The Journal of …, 2017‏ - Wiley Online Library
Objective The purpose of this cross‐sectional study was to assess the sociodemographics,
disease burden, and treatment patterns of patients with episodic and chronic migraine in the …