BODIPY-based probes for the fluorescence imaging of biomolecules in living cells

T Kowada, H Maeda, K Kikuchi - Chemical Society Reviews, 2015 - pubs.rsc.org
Fluorescence imaging techniques have been widely used to visualize biological molecules
and phenomena. In particular, several studies on the development of small-molecule …

Fluorescent indicators based on BODIPY

N Boens, V Leen, W Dehaen - Chemical Society Reviews, 2012 - pubs.rsc.org
This critical review covers the advances made using the 4-bora-3a, 4a-diaza-s-indacene
(BODIPY) scaffold as a fluorophore in the design, synthesis and application of fluorescent …

Structural modification strategies for the rational design of red/NIR region BODIPYs

H Lu, J Mack, Y Yang, Z Shen - Chemical Society Reviews, 2014 - pubs.rsc.org
This review focuses on classifying different types of long wavelength absorbing BODIPY
dyes based on the wide range of structural modification methods that have been adopted …

Synthesis of BODIPY dyes through postfunctionalization of the boron dipyrromethene core

N Boens, B Verbelen, MJ Ortiz, L Jiao… - Coordination Chemistry …, 2019 - Elsevier
Fluorophores based on the 4-bora-3a, 4a-diaza-s-indacene (aka boron dipyrromethene,
boron dipyrrin, or BODIPY) platform have found diverse applications in different fields of …

Fluorescent probe strategy for live cell distinction

X Liu, YT Chang - Chemical Society Reviews, 2022 - pubs.rsc.org
Live cell discrimination is the first and essential step to understand complex biosystems.
Conventional cell discrimination involving various antibodies relies on selective surface …

Combinatorial strategies in fluorescent probe development

M Vendrell, D Zhai, JC Er, YT Chang - Chemical reviews, 2012 - ACS Publications
The need for understanding essential recognition events in chemistry and biology has
directed considerable efforts toward the development of chemical probes. Fluorescent …

Bright building blocks for chemical biology

LD Lavis, RT Raines - ACS chemical biology, 2014 - ACS Publications
Small-molecule fluorophores manifest the ability of chemistry to solve problems in biology.
As we noted in a previous review (Lavis, LD; Raines, RT ACS Chem. Biol. 2008, 3, 142 …

Rhodium (III)-catalyzed arene and alkene C− H bond functionalization leading to indoles and pyrroles

DR Stuart, P Alsabeh, M Kuhn… - Journal of the American …, 2010 - ACS Publications
Recently, the rhodium (III)-complex [Cp* RhCl2] 2 1 has provided exciting opportunities for
the efficient synthesis of aromatic heterocycles based on a rhodium-catalyzed C− H bond …

The design and bioimaging applications of NIR fluorescent organic dyes with high brightness

J Wu, Z Shi, L Zhu, J Li, X Han, M Xu… - Advanced Optical …, 2022 - Wiley Online Library
Due to the merits of decreased photon attenuation, autofluorescence, and scattering, the
near‐infrared (NIR, 700–1700 nm) region is an important window in the field of biomedicine …

Near-infrared fluorescent probes as imaging and theranostic modalities for amyloid-beta and tau aggregates in Alzheimer's disease

H Rai, S Gupta, S Kumar, J Yang… - Journal of Medicinal …, 2022 - ACS Publications
A person suspected of having Alzheimer's disease (AD) is clinically diagnosed for the
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …