Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues
Dendrimers are the emerging polymeric architectures that are known for their defined
structures, versatility in drug delivery and high functionality whose properties resemble with …
structures, versatility in drug delivery and high functionality whose properties resemble with …
Surface-engineered dendrimers in gene delivery
J Yang, Q Zhang, H Chang, Y Cheng - Chemical reviews, 2015 - ACS Publications
1. DENDRIMERS AND GENE DELIVERY Gene therapy represents a promising option for
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …
Role of integrated cancer nanomedicine in overcoming drug resistance
Cancer remains a major killer of mankind. Failure of conventional chemotherapy has
resulted in recurrence and development of virulent multi drug resistant (MDR) phenotypes …
resulted in recurrence and development of virulent multi drug resistant (MDR) phenotypes …
Dendrimers in combination with natural products and analogues as anti-cancer agents
For the first time, an overview of dendrimers in combination with natural products and
analogues as anti-cancer agents is presented. This reflects the development of drug delivery …
analogues as anti-cancer agents is presented. This reflects the development of drug delivery …
A concise review on cancer treatment methods and delivery systems
The ultimate purpose of current cancer research is to develop a comprehensive treatment for
cancer. Recent studies have shown an increased interest in investigating the capacity of …
cancer. Recent studies have shown an increased interest in investigating the capacity of …
UTMD-promoted co-delivery of gemcitabine and miR-21 inhibitor by dendrimer-entrapped gold nanoparticles for pancreatic cancer therapy
L Lin, Y Fan, F Gao, L **, D Li, W Sun, F Li… - …, 2018 - pmc.ncbi.nlm.nih.gov
Conventional chemotherapy of pancreatic cancer (PaCa) suffers the problems of low drug
permeability and inherent or acquired drug resistance. Development of new strategies for …
permeability and inherent or acquired drug resistance. Development of new strategies for …
Peptide vectors for the nonviral delivery of nucleic acids
JAN Hoyer, I Neundorf - Accounts of chemical research, 2012 - ACS Publications
Over the past two decades, gene therapy has garnered tremendous attention and is
heralded by many as the ultimate cure to treat diseases such as cancer, viral infections, and …
heralded by many as the ultimate cure to treat diseases such as cancer, viral infections, and …
Engineering bone tissue from human embryonic stem cells
D Marolt, IM Campos, S Bhumiratana, A Koren… - Proceedings of the …, 2012 - pnas.org
In extensive bone defects, tissue damage and hypoxia lead to cell death, resulting in slow
and incomplete healing. Human embryonic stem cells (hESC) can give rise to all specialized …
and incomplete healing. Human embryonic stem cells (hESC) can give rise to all specialized …
Functionalized PAMAM constructed nanosystems for biomacromolecule delivery
Polyamidoamines (PAMAMs) are a class of dendrimer with monodispersity and controlled
topology, which can deliver biologically active macromolecules (eg, genes and proteins) to …
topology, which can deliver biologically active macromolecules (eg, genes and proteins) to …
Non-viral gene activated matrices for mesenchymal stem cells based tissue engineering of bone and cartilage
S Raisin, E Belamie, M Morille - Biomaterials, 2016 - Elsevier
Recent regenerative medicine and tissue engineering strategies for bone and cartilage
repair have led to fascinating progress of translation from basic research to clinical …
repair have led to fascinating progress of translation from basic research to clinical …