Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy

H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022‏ - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

Recent advances in contrast-enhanced photoacoustic imaging: overcoming the physical and practical challenges

W Choi, B Park, S Choi, D Oh, J Kim, C Kim - Chemical Reviews, 2023‏ - ACS Publications
For decades now, photoacoustic imaging (PAI) has been investigated to realize its potential
as a niche biomedical imaging modality. Despite its highly desirable optical contrast and …

J‐aggregation strategy toward potentiated NIR‐II fluorescence bioimaging of molecular fluorophores

X Hu, C Zhu, F Sun, Z Chen, J Zou, X Chen… - Advanced …, 2024‏ - Wiley Online Library
Molecular fluorophores emitting in the second near‐infrared (NIR‐II, 1000–1700 nm)
window with strong optical harvesting and high quantum yields hold great potential for in …

NIR-II light in clinical oncology: opportunities and challenges

Z Zhang, Y Du, X Shi, K Wang, Q Qu, Q Liang… - Nature Reviews …, 2024‏ - nature.com
Novel strategies utilizing light in the second near-infrared region (NIR-II; 900–1,880 nm
wavelengths) offer the potential to visualize and treat solid tumours with enhanced precision …

Versatile types of inorganic/organic NIR-IIa/IIb fluorophores: from strategic design toward molecular imaging and theranostics

Y Liu, Y Li, S Koo, Y Sun, Y Liu, X Liu, Y Pan… - Chemical …, 2021‏ - ACS Publications
In vivo imaging in the second near-infrared window (NIR-II, 1000–1700 nm), which enables
us to look deeply into living subjects, is producing marvelous opportunities for biomedical …

Molecular imaging and disease theranostics with renal-clearable optical agents

P Cheng, K Pu - Nature Reviews Materials, 2021‏ - nature.com
Optical imaging in disease diagnosis and treatment benefits from high spatiotemporal
resolution and the availability of numerous optical agents. However, many optical imaging …

The chemistry of organic contrast agents in the NIR‐II window

J Mu, M **ao, Y Shi, X Geng, H Li… - Angewandte Chemie …, 2022‏ - Wiley Online Library
Optical imaging, especially fluorescence and photoacoustic imaging, is a non‐invasive
imaging approach with high spatial and temporal resolution and high sensitivity, compared …

Advanced fluorescence imaging technology in the near-infrared-II window for biomedical applications

C Li, G Chen, Y Zhang, F Wu… - Journal of the American …, 2020‏ - ACS Publications
Fluorescence imaging has become a fundamental tool for biomedical applications;
nevertheless, its intravital imaging capacity in the conventional wavelength range (400–950 …

Aggregation‐induced emission luminogens for in vivo molecular imaging and theranostics in cancer

P Cen, J Huang, C **, J Wang, Y Wei, H Zhang… - …, 2023‏ - Wiley Online Library
Cancer is one of the most fatal diseases for decades. Aggregation‐induced emission
luminogens (AIEgens) have been recently used as molecular imaging or therapeutic agents …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020‏ - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …