The basal ganglia and the cerebellum: nodes in an integrated network

AC Bostan, PL Strick - Nature Reviews Neuroscience, 2018 - nature.com
The basal ganglia and the cerebellum are considered to be distinct subcortical systems that
perform unique functional operations. The outputs of the basal ganglia and the cerebellum …

[HTML][HTML] The anatomical basis for dystonia: the motor network model

HA **nah, V Neychev, EJ Hess - Tremor and other hyperkinetic …, 2017 - ncbi.nlm.nih.gov
Background The dystonias include a clinically and etiologically very diverse group of
disorders. There are both degenerative and non-degenerative subtypes resulting from …

Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis

J Grandjean, C Canella, C Anckaerts, G Ayrancı… - Neuroimage, 2020 - Elsevier
Preclinical applications of resting-state functional magnetic resonance imaging (rsfMRI) offer
the possibility to non-invasively probe whole-brain network dynamics and to investigate the …

The cerebellum and dystonia

M Bologna, A Berardelli - Handbook of clinical neurology, 2018 - Elsevier
Dystonia is a heterogeneous disorder characterized by involuntary muscle contractions,
twisting movements, and abnormal postures in various body regions. It is widely accepted …

Diffusion magnetic resonance imaging-derived free water detects neurodegenerative pattern induced by interferon-γ

M Febo, PD Perez, C Ceballos-Diaz… - Brain Structure and …, 2020 - Springer
Imaging biomarkers for immune activation may be valuable for early-stage detection,
therapeutic testing, and research on neurodegenerative conditions. In the present study, we …

Functional networks and network perturbations in rodents

KH Chuang, FA Nasrallah - Neuroimage, 2017 - Elsevier
Synchronous low-frequency oscillation in the resting human brain has been found to form
networks of functionally associated areas and hence has been widely used to map the …

Structural magnetic resonance imaging in dystonia: A systematic review of methodological approaches and findings

CL MacIver, CMW Tax, DK Jones… - European journal of …, 2022 - Wiley Online Library
Background and purpose Structural magnetic resonance techniques have been widely
applied in neurological disorders to better understand tissue changes, probing …

The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia

ZF Caffall, BJ Wilkes, R Hernández-Martinez… - Science translational …, 2021 - science.org
Dystonias are a group of chronic movement–disabling disorders for which highly effective
oral medications or disease-modifying therapies are lacking. The most effective treatments …

Evaluation of an adoptive cellular therapy-based vaccine in a transgenic mouse model of α-synucleinopathy

WT Chu, J Hall, A Gurrala, A Becsey… - ACS Chemical …, 2022 - ACS Publications
Aggregated α-synuclein, a major constituent of Lewy bodies plays a crucial role in the
pathogenesis of α-synucleinopathies (SPs) such as Parkinson's disease (PD). PD is affected …

DYT-TOR1A dystonia: an update on pathogenesis and treatment

Y Fan, Z Si, L Wang, L Zhang - Frontiers in Neuroscience, 2023 - frontiersin.org
DYT-TOR1A dystonia is a neurological disorder characterized by involuntary muscle
contractions and abnormal movements. It is a severe genetic form of dystonia caused by …