SARS‐CoV‐2 nucleocapsid: Biological functions and implication for disease diagnosis and vaccine design

F Maghsood, A Ghorbani, H Yadegari… - Reviews in Medical …, 2023 - Wiley Online Library
Abstract The coronavirus disease 2019 (COVID‐19) pandemic is transmitted by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and has affected millions of …

COV2Var, a function annotation database of SARS-CoV-2 genetic variation

Y Feng, J Yi, L Yang, Y Wang, J Wen… - Nucleic acids …, 2024 - academic.oup.com
The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has resulted in the loss
of millions of lives and severe global economic consequences. Every time SARS-CoV-2 …

Impact of mutations on the stability of SARS-CoV-2 nucleocapsid protein structure

N Muradyan, V Arakelov, A Sargsyan, A Paronyan… - Scientific Reports, 2024 - nature.com
The nucleocapsid (N) protein of SARS-CoV-2 is known to participate in various host cellular
processes, including interferon inhibition, RNA interference, apoptosis, and regulation of …

Modulation of biophysical properties of nucleocapsid protein in the mutant spectrum of SARS-CoV-2

A Nguyen, H Zhao, D Myagmarsuren, S Srinivasan… - Elife, 2024 - elifesciences.org
Genetic diversity is a hallmark of RNA viruses and the basis for their evolutionary success.
Taking advantage of the uniquely large genomic database of SARS-CoV-2, we examine the …

SARS‐CoV‐2 biology and variants: anticipation of viral evolution and what needs to be done

R Luo, A Delaunay‐Moisan, K Timmis… - Environmental …, 2021 - Wiley Online Library
The global propagation of SARS‐CoV‐2 and the detection of a large number of variants,
some of which have replaced the original clade to become dominant, underscores the fact …

ORF3c is expressed in SARS‐CoV‐2‐infected cells and inhibits innate sensing by targeting MAVS

M Müller, A Herrmann, S Fujita, K Uriu, C Kruth… - EMBO …, 2023 - embopress.org
Most SARS‐CoV‐2 proteins are translated from subgenomic RNAs (sgRNAs). While the
majority of these sgRNAs are monocistronic, some viral mRNAs encode more than one …

[HTML][HTML] SARS-CoV-2 Variants: Genetic Insights, Epidemiological Tracking, and Implications for Vaccine Strategies

FS Alhamlan, AA Al-Qahtani - International Journal of …, 2025 - pmc.ncbi.nlm.nih.gov
The emergence of SARS-CoV-2 variants has significantly impacted the global response to
the COVID-19 pandemic. This review examines the genetic diversity of SARS-CoV-2 …

Follow-up investigation and detailed mutational characterization of the SARS-CoV-2 Omicron variant lineages (BA. 1, BA. 2, BA. 3 and BA. 1.1)

Q Abbas, A Kusakin, K Sharrouf, S Jyakhwo… - biorxiv, 2022 - biorxiv.org
Aided by extensive protein mutations, the SARS-CoV-2 Omicron (B. 1.1. 529) variant
overtook the previously dominant Delta variant and rapidly spread around the world. It was …

[HTML][HTML] Multifaceted assessment of wastewater-based epidemiology for SARS-CoV-2 in selected urban communities in Davao City, Philippines: a pilot study

MCB Otero, LAE Murao, MAG Limen… - International journal of …, 2022 - mdpi.com
Over 60 countries have integrated wastewater-based epidemiology (WBE) in their COVID-
19 surveillance programs, focusing on wastewater treatment plants (WWTP). In this paper …

Variants in SARS-CoV-2 associated with mild or severe outcome

JD Voss, M Skarzynski, EM McAuley… - … medicine, and public …, 2021 - academic.oup.com
Introduction The coronavirus disease 2019 (COVID-19) pandemic is a global public health
emergency causing a disparate burden of death and disability around the world. The viral …