The human T-cell leukemia virus type 1 (HTLV-1), identified as the first human oncogenic
retrovirus 30 years ago, is not an ubiquitous virus. HTLV-1 is present throughout the world …

Epidemiologic aspects of human T-lymphotropic virus type I (HTLV-I) infection have been
thoroughly studied over the course of approximately 25 years since its first description. The …

Comparative studies of the nucleotide sequences of ribosomal RNA (rRNA) genes provide a
means for analyzing phylogenetic relationships over a wide range of taxonomic levels …

We applied the polymerase chain reaction to detection of the pathogenic protozoan
Toxoplasma gondii based on our identification of a 35-fold-repetitive gene (the B1 gene) as …

Since the ftrst report of specific DNA amplification using the polymerase chain reaction
(PCR) in 1985, the number of different applications has grown steadily, as have the …

The in vitro amplification of biologically important nucleic acids has proceeded principally by
a strategy of DNA replication. Polymerase chain reaction was the first such protocol to …

Isothermal nucleic acid amplification of target RNA or DNA sequences is accomplished by
the simultaneous enzymatic activity of AMV reverse transcriptase, T7 RNA polymerase and …

▪ Objective: To conduct neurologic, immunologic, and virologie studies in patients with a
chronic debilitating illness of acute onset.▪ Design: Cohort study with comparison to …

Advances in nucleic acid technology during the past five years have yielded practical probe-
based assays for diagnosing infectious and genetic diseases. Although the assays are …

The PCR, like recombinant DNA technology, has had an enormous impact in both basic and
diagnostic aspects of molecular biology because it can produce large amounts of a specific …